|Present||Professor, Nova Southeastern University ‐ College of Health Care Sciences|
Professional Service and Affiliations
|Present||Member, Florida ARES Network||Present||Council Member, Florida Academy of Sciences||Present||Member, Florida Occupation Therapy Association||Present||Member, Gulf Coast Hurricane Network||Present||Member, Human Anatomy and Physiology Society||Volunteer, Florida Junior Academy of Sciences program||Principal Investigator, The NSF and NIH multi-year grants|
|1982 - 1983||M.S., University of Florida ‐ Molecular Biology|
|1978 - 1982||B.S., University of Florida ‐ Zoology/Chemistry|
|1977 - 1978||A.A, Palm Beach State College|
An NIH and NSF Funded Program in Biological Research for Community College Students The Journal of the National Collegiate Honors Council
In a program supported by grants from the National Institutes of Health and the National Science Foundation, selected students in biology courses at Valencia Community College actively pursue the scientific method in a series of ...
Downregulation of Protein Kinase C and Insulin Stimulated 2-Deoxyglucose uptake in Rat Adipocytes by Phorbol Esters, Glucose and Insulin. Diabetes
Phorbol esters translocatively activate and subsequently downregulate protein kinase C and insulin-stimulated glucose uptake in rat adipocytes. This study examined the possibility that other translocative activators of protein kinase C in rat adipocytes, e.g., insulin ...
Effect of Insulin and phorbol esters on MARKS phosphorylation in rat adipocytes, rat soleus muscle and BC3H-1 myocytes Biochemistry Journal
membrane-associated protein kinase C (PKC) in rat adipocytes [1,2]. These increases appear to be due to translocation of PKC from cytosol to the membrane fraction, a process that may reflect activation of the enzyme. Insulin-induced ...
Effects of Insulin and Phorbol Esters on Subcellular distribution of Protein Kinase C isoforms in Rat Adipocytes Biochemistry Journal
Effects of insulin and phorbol esters on subcellular distribution of protein kinase C (PKC) isoforms were examined in rat adipocytes. Both agonists provoked rapid decreases in cytosolic, and/or increases in membrane, immunoreactive PKC-alpha, PKC-beta, PKC-gamma, ...
Effects of Insulin on Diacylglycerol, Protein Kinase C and Glucose Transport in Rat Skeletal Muscle. Endocrinology
Insulin treatment in vivo provoked rapid dose-related increases in diacylglycerol content and/or translocation of protein kinase-C (PKC) from cytosol to membranes in rat soleus and gastrocnemius muscles. These effects were apparent with 1) insulin doses ...
Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome The Journal of Lipid Research
Smith-Lemli-Opitz syndrome (SLOS) is a recessive disease typified by 7-dehydrocholesterol (7DHC) accumulation and depletion of cholesterol. Because cholesterol is a primary component of detergent-resistant membrane domains ("rafts"), we examined the compatibility of 7DHC with raft ...
Insulin Translocates PKC-ε and Phorbol esters induce and persistantly translocates PKC-β2 in BC3H-1 myocytes Cellular Signalling
Initial studies suggested that insulin increases diacylglycerol and activates protein kinase C (PKC) in BC3H-1 myocytes. In these earlier studies, insulin was found to translocate PKC-β, but the presence of PKC-ϵ was not appreciated. More ...