|Present||Associate Professor, Iowa State University ‐ Department of Biochemistry, Biophysics and Molecular Biology|
|2003 - 2008||Postdoctoral Fellow, Pennsylvania State University - Main Campus|
|2002||PhD, Iowa State University ‐ Biochemistry|
|1997||B.S., North Dakota State University - Main Campus ‐ Biotechnology|
4112 Molecular Biology Building
Dept. of Biochemistry, Biophysics & Molecular Biology
Iowa State University
Ames, IA 50011
Peer-Reviewed Articles (21)
Crystallization and preliminary X-ray analysis of the Plasmodium falciparum apicoplast ...
Acta Crystallographica Section F:Structural Biology Communications (2015)
Infection by the parasite Plasmodium falciparum is the leading cause of malaria in humans. The parasite has a unique and ...
Mechanism of Action of Escherichia coli Phosphoribosylaminoimidazolesuccinocarboxamide Synthetase
The conversion of ATP, l-aspartate, and 5-aminoimidazole-4-carboxyribonucleotide (CAIR) to 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate by phosphoribosylaminoimidazolesuccinocarboxamide synthetase (SAICAR synthetase) ...
Origin of Cooperativity in the Activation of Fructose-1,6-bisphosphatase by ...
Journal of Biological Chemistry (2004)
Fructose-1,6-bisphosphatase requires a divalent metal cation for catalysis, Mg2+being its most studied activator. Phosphatase activity increases sigmoidally with the concentration ...
Hybrid Tetramers of Porcine Liver Fructose-1,6-bisphosphatase Reveal Multiple Pathways ...
Journal of Biological Chemistry (2002)
Fructose-1,6-bisphosphatase is a square planar tetramer of identical subunits, which exhibits cooperative allosteric inhibition of catalysis by AMP. Protocols for ...
The N-terminal Segment of Recombinant Porcine Fructose-1,6-bisphosphatase Participates in ...
Journal of Biological Chemistry (2001)
Residues 1–10 of porcine fructose-1,6-bisphosphatase (FBPase) are poorly ordered or are in different conformations, sensitive to the state of ligation ...