SelectedWorks - Aileen Keating

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Selected Works of Aileen Keating

Associate Professor of Animal Science

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About Aileen Keating

Present	Associate Professor of Animal Science, Iowa State University
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Animal Sciences

Articles (42)

Article

Effects of Genetic Selection for Residual Feed Intake on Behavioral ...

Applied Animal Behaviour Science (2014)

Jessica D. Colpoys, Caitlyn Abell, Jennifer M. Young, Aileen F. Keating, et al.

Increasing feed efficiency in swine is important for increasing sustainable food production and profitability for producers; therefore, this is often ...

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Article

Involvement of a volatile metabolite during phosphoramide mustard-induced ovotoxicity

Toxicology and Applied Pharmacology (2014)

Jill A. Madden, Patricia B. Hoyer, Patrick J. Devine and Aileen F. Keating

The finite ovarian follicle reserve can be negatively impacted by chemical exposures including the anti-neoplastic agent, cyclophosphamide (CPA). CPA requires ...

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Article

Acute 7,12-dimethylbenz[a]anthracene exposure causes differential concentration-dependent follicle ...

Toxicology and Applied Pharmacology (2014)

Jill A. Madden, Patricia B. Hoyer, Patrick J. Devine and Aileen F. Keating

Chronic exposure to the polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene (DMBA), generated during combustion of organic matter including cigarette smoke, depletes all ...

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Article

Impact of obesity on ovotoxicity induced by 7,12-dimethylbenz[a ...

Biology of Reproduction (2014)

Jackson Nteeba, Shanthi Ganesan and Aileen F. Keating

Insulin, elevated during obesity, regulates xenobiotic biotransformation enzymes, potentially through phosphatidylinositol 3-kinase (PI3K) signaling, in extraovarian tissues. PI3K regulates oocyte ...

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Article

Impact of 7,12-dimethylbenz[a]anthracene exposure on connexin gap ...

Toxicology and Applied Pharmacology (2014)

Shanthi Ganesan and Aileen F. Keating

7,12-dimethylbenz[a]anthracene (DMBA) destroys ovarian follicles in a concentration-dependent manner. The impact of DMBA on connexin (CX) proteins that mediate communication ...

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Article

High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling ...

Reproductive Toxicology (2013)

J. Nteeba, J. W. Ross, J. W. Perfield and A. F. Keating

Insulin regulates ovarian phosphatidylinositol-3-kinase (PI3K) signaling, important for primordial follicle viability and growth activation. This study investigated diet-induced obesity impacts ...

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Article

7,12-Dimethylbenz[a]anthracene exposure induces the DNA repair response ...

Toxicology and Applied Pharmacology (2013)

Shanthi Ganesan, Poulomi Bhattacharya and Aileen F. Keating

7,12-Dimethylbenz[a]anthracene (DMBA) destroys ovarian follicles at all stages of development. This study investigated DMBA-induced DNA double strand break (DSB) formation ...

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Article

Intestinal integrity, endotoxin transport and detoxification in pigs divergently selected ...

Journal of Animal Science (2013)

Venkatesh Mani, A. J. Harris, Aileen F. Keating, Thomas E. Weber, et al.

Microbes and microbial components potentially impact the performance of pigs through immune stimulation and altered metabolism. These immune modulating factors ...

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Article

Glutathione S-transferase class mu regulation of apoptosis signal-regulating kinase 1 ...

Toxicology and Applied Pharmacology (2013)

Poulomi Bhattacharya, Jill A. Madden, Nivedita Sen, Patricia B. Hoyer, et al.

4-vinylcyclohexene diepoxide (VCD) destroys ovarian primordial and small primary follicles via apoptosis. In mice, VCD exposure induces ovarian mRNA expression ...

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Article

Impact of environmental exposures on ovarian function and role of ...

Toxicology and Applied Pharmacology (2012)

Poulomi Bhattacharya and Aileen F. Keating

The mammalian ovary is a heterogeneous organ, and contains oocyte-containing follicles at varying stages of development. The most immature follicular ...

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Article

Protective role for ovarian glutathione S-transferase isoform pi during 7 ...

Toxicology and Applied Pharmacology (2012)

Poulomi Bhattacharya and Aileen F. Keating

7,12-dimethylbenz[a]anthracene (DMBA) destroys ovarian follicles at all developmental stages. This study investigated a role for the glutathione S-transferase (Gst) isoforms ...

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Article

A Comparison of Inflammatory and Oxidative Stress Markers in Adipose ...

Experimental Diabetes Research (2012)

Karen J. Nickelson, Kelly L. Stromsdorfer, R. Taylor Pickering, Tzu-Wen Liu, et al.

Expansion of intra-abdominal adipose tissue and the accompanying inflammatory response has been put forward as a unifying link between obesity ...

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Article

Ovarian expressed microsomal epoxide hydrolase: Role in detoxification of 4-vinylcyclohexene ...

Toxicology and Applied Pharmacology (2012)

Poulomi Bhattacharya, Nivedita Sen, Patricia B. Hoyer and Aileen F. Keating

4-vinylcyclohexene diepoxide (VCD) is a metabolite of 4-vinylcyclohexene (VCH) which has the potential to be formed in the ovary through ...

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Article

Inhibition of PIK3 Signaling Pathway Members by the Ovotoxicant 4-Vinylcyclohexene ...

Biology of Reproduction (2011)

Aileen F. Keating, Shannon M. Fernandez, Connie J. Mark-Kappeler, Nivedita Sen, et al.

4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that specifically destroys primordial and small primary follicles in the ovaries of rats and ...

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Article

Ovarian metabolism of xenobiotics

Experimental Biology and Medicine (2011)

Poulomi Bhattacharya and Aileen F. Keating

At birth, the mammalian ovary contains a finite number of primordial follicles, which once depleted, cannot be replaced. Xenobiotic exposures ...

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Article

Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development ...

Toxicology and Applied Pharmacology (2010)

Connie J. Mark-Kappeler, Nivedita Sen, Aileen F. Keating, I. Glenn Sipes, et al.

Anti-Müllerian hormone (AMH) is produced by granulosa cells in primary to small antral follicles of the adult ovary and helps ...

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Article

Dual protective role for Glutathione S-transferase class pi against VCD-induced ...

Toxicology and Applied Pharmacology (2010)

Aileen F. Keating, Nivedita Sen, I. Glenn Sipes and Patricia B. Hoyer

The occupational chemical 4-vinylcyclohexene diepoxide (VCD) selectively destroys ovarian small pre-antral follicles in rats and mice via apoptosis. Detoxification of ...

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Contribution to Book

Mechanisms of Ovarian Atresia Induced by Xenobiotic Exposures

Basic Gynecology - Some Related Issues (2012)

Jason W. Ross and Aileen F. Keating

The focus of this chapter is the mechanisms of apoptosis that occur during “normal” (physiologically-induced) or “abnormal” (chemical- or pathology-induced) ...

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Presentation

Developmental Origins of Ovarian Disorder: Impact of Maternal Lean Gestational ...

Biology of Reproduction (2019)

Kendra L. Clark, Omonseigho O. Talton, Shanthi Ganesan, Laura C. Schulz, et al.

Gestational diabetes mellitus (GDM) is an obstetric disorder affecting approximately 10% of pregnancies. The 4HFHS (High Fat High Sucrose) mouse ...

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Presentation

Pelvic Organ Prolapse: An Industry-Wide Collaboration to Identify Putative Contributing ...

Proceedings of the 2018 ISU James D. McKean Swine Disease Conference (2018)

Amanda L. Chipman, Christopher J. Rademacher, Colin D. Johnson, Ken J Stalder, et al.

Sow mortality, specifically as the result of pelvic organ prolapse (POP), has significantly increased in the past five years in ...

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Presentation

Pelvic organ prolapse: An industry-wide collaboration to identify putative contributing ...

Animal Science Conference Proceedings and Presentations (2018)

Amanda Chipman, Chris Rademacher, Colin Johnson, Ken Stalder, et al.

Amanda Chipman explains some of the data collected in the Pelvic Organ Prolapse project conducted by the Iowa Pork Industry ...

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Presentation

Leaky Gut’s Contribution to Inefficient Nutrient Utilization

WCDS Advances in Dairy Technology (2017)

S. K. Kvidera, E. A. Horst, M. Al-Qaisi, M. J. Dickson, et al.

There are a variety of situations in an animal’s life when nutrient utilization is reprioritized from productive towards agriculturally unproductive ...

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Article

Approachability to a Human in Gilts Divergently Selected for Feed ...

Animal Industry Report (2015)

Johanna Sholar, Jessica D. Colpoys, Nicholas K. Gabler, Aileen F. Keating, et al.

The objective of this study was to evaluate approachability of gilts divergently selected for residual feed intake (RFI) to a ...

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Article

Genome-Wide Association Analyses of Biological Responses to Heat Stress in ...

Animal Industry Report (2015)

Kwan-Suk Kim, Eui-Soo Kim, Jacob T. Seibert, Aileen F. Keating, et al.

With genetic selection for rapid, lean tissue accretion, pigs are becoming increasingly sensitive to heat stress (HS) due to their ...

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Article

Barrow Behavioral Responsiveness to a Human or Novel Object When ...

Animal Industry Report (2014)

Jessica D. Colpoys, Anna K. Johnson, Nicholas K. Gabler, Aileen F. Keating, et al.

The objective of this study was to determine if diet influences behavioral responsiveness to novel stimuli as assessed by human ...

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About Aileen Keating

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Disciplines

Articles (42)

Book Chapters (1)

Proceedings and Presentations (4)

Animal Industry Reports (8)