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Hussam A. Yacoub, DO

Physician

Disciplines

  • Medicine and Health Sciences
  • Neurology

Research Interests

  • 7/99-8/01 Thesis Research: Laboratory of Molecular Pharmacology, Department of Physiology and Pharmacology, MCP Hahnemann University School of Medicine, Philadelphia PA. • Thesis Objectives: To investigate molecular mechanisms mediating desensitization of the G protein coupled A1-Adenosine receptor in the brain and aged heart, and to determine whether such alterations contribute to tissue vulnerability during ischemic insult.
  • 8/97-6/99 Research Rotations at MCP Hahnemann University School of Medicine, Philadelphia, PA. • Center for Gene Therapy: Investigated the effect of tyrosine hydroxylase transfected primary rat astrocyte cultures on Parkinson’s disease rat models. • Department of Pharmacology & Physiology: Examined the effect of several pharmacological agents norepinephrine release in prepared young and aged rat heart synaptosomes. • Department of Neurobiology/Anatomy: Investigated the involvement of semaphorines in mediating growth of cerebellar neurite explants from the developing mouse brain.
  • Research Assistant at Lehigh University, Bethlehem, PA. •Thesis Objectives: Prepared organic compounds in an organic synthesis laboratory. Overall goal was to isolate an anion transport protein found in proximal convoluted tubule cells of rat kidney nephron.

Hina A. Sheikh, M.D.

Pathologist

Disciplines

  • Medicine and Health Sciences
  • Pathology

Research Interests

  • 5/2000-12/2000 • The Johns Hopkins University, Department of Pathology, Designed and constructed tissue micro-arrays of lung and breast cancers for simultaneous immunohistochemical analysis of multiple tumor samples. 6/2005 •Leiden University, Netherlands, Department of Dermatology, Studied histology and immunohistochemistry of cutaneous lymphomas. 2006 • University of Pittsburgh Division of Molecular Diagnostics, Compared IgH Biomed-2 multiplex PCR assay to in-house PCR assay for detection of immunoglobulin heavy chain gene rearrangement in B-cell lymphoid infiltrates. 2007 •University of Pittsburgh, Division of Molecular Diagnostics, Evaluated three different methods of DNA extraction from formalin-fixed paraffin-embedded skin specimens.