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Hussam A. Yacoub, DO, MS

Physician

Disciplines

  • Medicine and Health Sciences
  • Neurology

Research Interests

  • 7/99-8/01 Thesis Research: Laboratory of Molecular Pharmacology, Department of Physiology and Pharmacology, MCP Hahnemann University School of Medicine, Philadelphia PA. • Thesis Objectives: To investigate molecular mechanisms mediating desensitization of the G protein coupled A1-Adenosine receptor in the brain and aged heart, and to determine whether such alterations contribute to tissue vulnerability during ischemic insult.
  • 8/97-6/99 Research Rotations at MCP Hahnemann University School of Medicine, Philadelphia, PA. • Center for Gene Therapy: Investigated the effect of tyrosine hydroxylase transfected primary rat astrocyte cultures on Parkinson’s disease rat models. • Department of Pharmacology & Physiology: Examined the effect of several pharmacological agents norepinephrine release in prepared young and aged rat heart synaptosomes. • Department of Neurobiology/Anatomy: Investigated the involvement of semaphorines in mediating growth of cerebellar neurite explants from the developing mouse brain.
  • Research Assistant at Lehigh University, Bethlehem, PA. •Thesis Objectives: Prepared organic compounds in an organic synthesis laboratory. Overall goal was to isolate an anion transport protein found in proximal convoluted tubule cells of rat kidney nephron.

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  1. Medicine and Health Sciences
  2. Neurology

Discipline

    1. Medicine and Health Sciences
    2. Neurology
    3. Neurosciences 1
    4. Medical Neurobiology 1
    5. Medical Pathology 1

Research Interest

    1. 7/99-8/01 Thesis Research: Laboratory of Molecular Pharmacology, Department of Physiology and Pharmacology, MCP Hahnemann University School of Medicine, Philadelphia PA. • Thesis Objectives: To investigate molecular mechanisms mediating desensitization of the G protein coupled A1-Adenosine receptor in the brain and aged heart, and to determine whether such alterations contribute to tissue vulnerability during ischemic insult. 1
    2. 8/97-6/99 Research Rotations at MCP Hahnemann University School of Medicine, Philadelphia, PA. • Center for Gene Therapy: Investigated the effect of tyrosine hydroxylase transfected primary rat astrocyte cultures on Parkinson’s disease rat models. • Department of Pharmacology & Physiology: Examined the effect of several pharmacological agents norepinephrine release in prepared young and aged rat heart synaptosomes. • Department of Neurobiology/Anatomy: Investigated the involvement of semaphorines in mediating growth of cerebellar neurite explants from the developing mouse brain. 1
    3. Autism 1
    4. Chiari Malformation 1
    5. July 2016 to current, Key Opinion Leader, for Study 364 for Long-term, open-label, Phase III trial of ESL (eslicarbazepine acetate) _Aptiom in children and adolescents (4–17 years) with Partial Onset Seizures. Ltd.Sunovion Pharmaceuticals Inc. Contact person: Romy Nocera PhD Director, Medical Science Liaison Sunovion Pharmaceuticals 1

Organization

    1. LVPG Neurology 2
    2. Snooze News 1
    3. Health Network Laboratories 1
    4. Department of Neurology 1
    5. Department of Pathology & laboratory Medicine 1

Position

    1. Physician 4