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About Ruth C. Borghaei

Dr. Ruth Borghaei is a Professor in the Department of Biomedical Sciences. She is Director of the Molecular Basis of Medicine course in the Masters in Biomedical Sciences program and also teaches molecular biology and genetics to those students and to first-year DO students. Dr. Borghaei's research interest is in the homeostatic regulation of gene expression, particularly in response to inflammation.
Dr. Borghaei has also served as reviewer for a number of peer-reviewed journals and grant-making panels for the NIH and other organizations.

Positions

Present Professor of Biochemistry and Molecular Biology, Dept. of Bio-Medical Sciences, Philadelphia College of Osteopathic Medicine Department of Bio-Medical Sciences
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Disciplines



Grants

2015 - Present Regulation of DNA methylation and demethylation by inflammatory cytokines
NIH/NIDCR
Role: PI
2010 - 2011 Effects of nicotine and glucose on production of inflammatory mediators in response to IL-1 and LPS in human gingival fibroblasts and CAL27 oral cancer cells
CCDA, PCOM
Role: PI
2004 - 2010 Transcriptional regulation of matrix metalloproteinase 3
NIH - R15 DE16277
Research Supplement to Promote Diversity in Health-related Research
Role: PI
1997 - 2003 IL-1 Regulation of MMP Genes in Human Gingival Fibroblasts
NIH - R29 DE12096-01
Supplement for Underrepresented Minorities
Role: PI
1995 - 1997 IL-1 Regulation of MMP Genes in Human Gingival Fibroblasts
NIH - RO3 DE11577-01
Role: PI
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Professional Service and Affiliations

Present Member, American Society for Biochemistry and Molecular Biology
Present Member, American Society of Genetics
Present Member, Sigma Xi - PCOM Chapter
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Courses

  • Genetics
  • Molecular Biology
  • Molecular Basis of Medicine

Education

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1992 PhD, Temple University School of Medicine ‐ Microbiology and Immunology
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1987 BS, University of Maine ‐ Microbiology
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Contact Information

P: 215-871-6454

Email:



Scholarly Articles (21)

Grants (4)