SelectedWorks - Rolando Garcia-Milian

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Selected Works of Rolando Garcia-Milian

Research and Education Support for Bioinformatics

I oversee the Bioinformatics Support Program of the Yale Medical Library. We provide access to the state-of-the-art bioinformatics software, training, consultations, and collaboration for projects that require high-throughput data analysis. Our office is located in the Yale Medical Library room L103

http://orcid.org/0000-0003-1557-566X

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About Rolando Garcia-Milian

I oversee the Bioinformatics Support Program of the Yale Medical Library. We provide access to the state-of-the-art bioinformatics software, training, consultations, and collaboration for projects that require high-throughput data analysis. Our office is located in the Yale Medical Library room L103

http://orcid.org/0000-0003-1557-566X

Present	Biomedical Sciences Research Support, Yale University
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Bioinformatics Guide

Articles (19)

Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response. (Rolando Garcia-Milian and Mahnaz Sahraei) The Journal of clinical investigation. (2019)

microRNA-21 (miR-21) is the most commonly upregulated miRNA in solid tumors. This cancer-associated microRNA (oncomiR) regulates various downstream effectors associated with tumor pathogenesis during all stages of carcinogenesis. In this study, we analyzed the function ...

Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber (Salmaan H Inayat-Hussain, Nicole C Deziel, Rolando Garcia-Milian, et al.) Environmental Research (2019)

Currently, there are >11,000 synthetic turf athletic fields in the United States and >13,000 in Europe. Concerns have been raised about exposure to carcinogenic chemicals resulting from contact with synthetic turf fields, particularly the infill material (“crumb ...

Resilience to Pain: A Peripheral Component Identified using induced Pluripotent Stem Cells and Dynamic Clamp (Malgorzata Mis, Carolina Gomis-Perez and Rolando Garcia-Milian) The Journal of neuroscience : the official journal of the Society for Neuroscience (2018)

Pain is a complex process that involves both detection in the peripheral nervous system and perception in the central nervous system. Individual-to-individual differences in pain are well-documented, but not well-understood. Here we capitalized on inherited erythromelalgia (IEM), ...

Data challenges of biomedical researchers in the age of omics (Rolando Garcia-Milian, Milica Vukmirovic and Denise Hersey) Peer J (2018)

BackgroundHigh-throughput technologies are rapidly generating large amounts of diverse omics data. Although this offers a great opportunity, it also poses great challenges as data analysis becomes more complex. The purpose of this study was to ...

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment (Salmaan H Inayat-Hussain, Vasilis Vasiliou, Rolando Garcia-Milian, et al.) Environment International (2018)

BACKGROUND: Recent trends have witnessed the global growth of unconventional oil and gas (UOG) production. Epidemiologic studies have suggested associations between proximity to UOG operations with increased adverse birth outcomes and cancer, though specific potential ...

Estrogen receptor-alpha isoforms are the main estrogen receptors expressed in Non-Small Cell Lung Carcinoma (Vasiliki Pelekanou and Rolando Garcia-Milian) Steroids (2018)

The expression profile of estrogen receptors (ER) in Non-Small Cell Lung Carcinoma (NSCLC) remains contradictory. Here we investigated protein and transcriptome expression of ERα wild type and variants. Tissue Micro-Arrays of 200 cases of NSCLC ...

Genome-wide significant, replicated and functional risk variants for Alzheimer's disease (Rolando Garcia-Milian) Journal of neural transmission (Vienna, Austria : 1996) (2017)

Genome-wide association studies (GWASs) have reported numerous associations between risk variants and Alzheimer's disease (AD). However, these associations do not necessarily indicate a causal relationship. If the risk variants can be demonstrated to be biologically ...

Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence (Lingjun Zuo, Rolando Garcia-Milian and Xingguang Luo) Genes (Basel) (2016)

It has been hypothesized that the nicotinic acetylcholine receptors (nAChRs) play important roles in nicotine dependence (ND) and influence the number of cigarettes smoked per day (CPD) in smokers. We compiled the associations between nicotinic ...

Health and safety during Canal construction In 100 Years of The Panama Canal. Celebrating the Centennial 1914- 2014 2014 (Rolando Garcia-Milian) (2014)

The use of Research Electronic Data Capture (REDCap) software to create a database of librarian-mediated literature searches. (Jennifer Lyon, Jennifer A Lyon, Hannah Norton, et al.) Medical reference services quarterly. (2014)

Expert-mediated literature searching, a keystone service in biomedical librarianship, would benefit significantly from regular methodical review. This article describes the novel use of Research Electronic Data Capture (REDCap) software to create a database of literature ...

Librarians as Part of Cross-Disciplinary, Multi-Institutional Team Projects: Experiences from the VIVO Collaboration (Rolando Garcia-Milian, Hannah Norton, Beth Auten, et al.) Science and technology libraries (2013)

Cross-disciplinary, team-based collaboration is essential for addressing today's complex research questions, and librarians are increasingly entering into such collaborations. This study identifies skills needed as librarians integrate into cross-disciplinary teams, based on the experiences of ...

Moving beyond the bookshelves. (Rolando Garcia-Milian and Hannah Norton) Medical Library Association (2013)

New technologies, the ubiquity of the Internet, and the superabundance of available information have given librarians new opportunities to reenvision their roles, service solutions, and collaborations in this evolving information environment. More than anything else, ...

The changing face of reference: biomedical and health information services in the classroom, clinic and beyond (Rolando Garcia-Milian) Medical Reference Services Quarterly (2012)

The presence of academic health sciences libraries on Facebook: the relationship between content and library popularity. (Rolando Garcia-Milian, Hannah Norton and Michele R. Tennant) Medical reference services quarterly (2012)

Social networks such as Facebook allow libraries to be proactive in reaching their users. While some libraries have popular Facebook pages, it remains unclear what attracts users to these pages. This study evaluates relationships between ...

Role of librarians in the development of community research networks. (Rolando Garcia-Milian) E-Science Portal for New England Librarians, (2011)

Molecular analysis of resistance to interferon in patients with laryngeal papillomatosis (Rolando Garcia-Milian) Cytokines Cellular & Molecular Therapy 5 (1999)

Genetic expression of the neural growth factor in the central nervous system. Evaluation of an experimental model of Alzheimer’s dementia (Rolando Garcia-Milian) Revista Neurologica 26 (1998)

Modulation of Human Papillomavirus-16 mRNA in cervical invasive carcinoma patients by alpha interferon therapy (Rolando Garcia-Milian) Journal of Interferon & Cytokine Research 16 (1996)

Interferon-alpha elicits downregulation of human papillomavirus 18 mRNA in HeLa cells by selective repression of endogenous viral transcription (Silvio E Perea, Omar Lopez-Ocejo, Rolando Garcia-Milian, et al.) Journal of interferon and cytokine research (1995)

We have reported that interferon-alpha inhibits HPV-18 mRNA in HeLa cells. Here we examine mechanisms by which IFN could modulate HPV expression. In northern blot experiments, we observed that interferon-alpha 2b treatment reduced HPV-18 mRNA ...

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment (Salmaan H Inayat-Hussain, Rolando Garcia-Milian, Vasilis Vasiliou, et al.) Environment International (2018)

BackgroundRecent trends have witnessed the global growth of unconventional oil and gas (UOG) production. Epidemiologic studies have suggested associations between proximity to UOG operations with increased adverse birth outcomes and cancer, though specific potential etiologic ...

Interview questionaire: Data Challenges of Biomedical Researchers in the Age of Omics (Rolando Garcia-Milian, Denise Hersey and Milica Vukmirovic) (2017)

Survey Instrument: Data Challenges of Biomedical Researchers in the Age of Omics (Rolando Garcia-Milian, Denise Hersey and Milica Vukmirovic) (2017)

Questionnaire used for the study: Peer teaching approach to bioinformatics training in a research-intensive institution (Rolando Garcia-Milian, Caitlin Meyer and Nur-Taz Rahman) (2020)

Questions used for the study Peer teaching approach to bioinformatics training in a research-intensive institution

Survey Data: Data Challenges of Biomedical Researchers in the Age of Omics (Rolando Garcia-Milian) (2018)

De-identified interviews for the study: Data Challenges of Biomedical Researchers in the Age of Omics (Rolando Garcia-Milian, Denise Hersey and Milica Vukmirovic) (2018)

Background: High-throughput technologies are rapidly generating large amounts of diverse omics data. Although this offers a great opportunity, it also poses great challenges as data analysis becomes more complex. The purpose of this study was ...