SelectedWorks - Michael Rosenblum MD

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Selected Works of Michael Rosenblum MD

Internal Medicine

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About Michael Rosenblum MD

Present	Internal Medicine, Baystate Health
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Medicine and Health Sciences

Baystate High Street Health Center Adult Medicine
140 High Street
C-Level
Springfield, MA 01199

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The Impact of Secondary Condom Interventions on the Interpretation of Results from HIV Prevention Trials (Stephen Shiboski, Michael Rosenblum and Nicholas P. Jewell) Statistical Communications in Infectious Diseases (2010)

Given the recent failure of a number of randomized trials to demonstrate effectiveness of proposed methods for prevention of sexual transmission of HIV, novel approaches to study design and analysis that address adherence and other ...

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OPTIMAL, TWO STAGE, ADAPTIVE ENRICHMENT DESIGNS FOR RANDOMIZED TRIALS USING SPARSE LINEAR PROGRAMMING (Michael Rosenblum, Xingyuan Fang and Han Liu) Johns Hopkins University, Dept. of Biostatistics Working Papers (2017)

Adaptive enrichment designs involve preplanned rules for modifying enrollment criteria based on accruing data in a randomized trial. We focus on designs where the overall population is partitioned into two predefined subpopulations, e.g., based on ...

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SENSITIVITY OF TRIAL PERFORMANCE TO DELAY OUTCOMES, ACCRUAL RATES, AND PROGNOSTIC VARIABLES BASED ON A SIMULATED RANDOMIZED TRIAL WITH ADAPTIVE ENRICHMENT (Tiachen Qian, Elizabeth Colantuoni, Aaron Fisher, et al.) Johns Hopkins University, Dept. of Biostatistics Working Papers (2016)

Adaptive enrichment designs involve rules for restricting enrollment to a subset of the population during the course of an ongoing trial. This can be used to target those who benefit from the experimental treatment. To ...

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INEQUALITY IN TREATMENT BENEFITS: CAN WE DETERMINE IF A NEW TREATMENT BENEFITS THE MANY OR THE FEW? (Emily Huang, Ethan Fang, Daniel Hanley, et al.) Johns Hopkins University, Dept. of Biostatistics Working Papers (2015)

The primary analysis in many randomized controlled trials focuses on the average treatment effect and does not address whether treatment benefits are widespread or limited to a select few. This problem affects many disease areas, ...

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ADAPTIVE ENRICHMENT DESIGNS FOR RANDOMIZED TRIALS WITH DELAYED ENDPOINTS, USING LOCALLY EFFICIENT ESTIMATORS TO IMPROVE PRECISION (Michael Rosenblum, Tianchen Qian, Yu Du, et al.) Johns Hopkins University, Dept. of Biostatistics Working Papers (2015)

Adaptive enrichment designs involve preplanned rules for modifying enrollment criteria based on accrued data in an ongoing trial. For example, enrollment of a subpopulation where there is sufficient evidence of treatment efficacy, futility, or harm ...

Linking digital natives with digital immigrants (Gina Luciano, Sudeep Kaur Aulakh and Michael Rosenblum) All Scholarly Works (2015)

Seeing is believing: Optimizing outpatient direct observation in the age of milestones (Sudeep Kaur Aulakh and Michael Rosenblum) All Scholarly Works (2015)

Clinic Design and Continuity in Internal Medicine Resident Clinics: Findings of the Educational Innovations Project Ambulatory Collaborative (Michael Rosenblum) All Scholarly Works (2015)

Background Many internal medicine (IM) programs have reorganized their resident continuity clinics to improve trainees' ambulatory experience. Downstream effects on continuity of care and other clinical and educational metrics are unclear. Methods This multi-institutional, cross-sectional ...

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LEVERAGING PROGNOSTIC BASELINE VARIABLES TO GAIN PRECISION IN RANDOMIZED TRIALS (Elizabeth Colantuoni and Michael Rosenblum) Leveragin Prognostic Baseline Variables to Gain Precision (2015)

We focus on estimating the average treatment effect in a randomized trial. If baseline variables are correlated with the outcome, then appropriately adjusting for these variables can improve precision. An example is the analysis of ...

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Adaptive, Group Sequential Designs that Balance the Benefits and Risks of Wider Inclusion Criteria (Michael Rosenblum, Brandon S Luber, Richard E Thompson, et al.) Adaptive Group Sequential Designs that Balance the Benefits and Risks of Expanding Inclusion Criteria (2015)

We propose a new class of adaptive randomized trial designs aimed at gaining the advantages of wider generalizability and faster recruitment, while mitigating the risks of including a population for which there is greater a ...

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A randomized controlled trial of mental health interventions for survivors of systematic violence in Kurdistan, Northern Iraq (Paul Bolton, Judith K. Bass, Goran Zangana, et al.) Open Access Publications by UMass Chan Authors (2014)

Background: Experiencing systematic violence and trauma increases the risk of poor mental health outcomes; few interventions for these types of exposures have been evaluated in low resource contexts. The objective of this randomized controlled trial ...

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ENHANCED PRECISION IN THE ANALYSIS OF RANDOMIZED TRIALS WITH ORDINAL OUTCOMES (Iván Díaz, Elizabeth Colantuoni and Michael Rosenblum) Johns Hopkins University, Dept. of Biostatistics Working Papers (2014)

We present a general method for estimating the effect of a treatment on an ordinal outcome in randomized trials. The method is robust in that it does not rely on the proportional odds assumption. Our ...

Bridging the digital chasm: Linking digital natives with digital immigrants (Sudeep Kaur Aulakh, Gina Luciano, Michael Rosenblum, et al.) All Scholarly Works (2014)

Determinants of Patient Satisfaction in Internal Medicine Resident Continuity Clinics: Findings of the Educational Innovations Project Ambulatory Collaborative (Michael Rosenblum) All Scholarly Works (2014)

Background Many internal medicine programs have reorganized their resident continuity clinics to improve the ambulatory care experience for residents. The effect of this redesign on patient satisfaction is largely unknown. Methods Our multi-institutional, cross-sectional study ...

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INTERADAPT -- AN INTERACTIVE TOOL FOR DESIGNING AND EVALUATING RANDOMIZED TRIALS WITH ADAPTIVE ENROLLMENT CRITERIA (Aaron Joel Fisher, Harris Jaffee and Michael Rosenblum) Johns Hopkins University, Dept. of Biostatistics Working Papers (2014)

The interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer tangible benefits compared to standard designs, ...

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TARGETED MAXIMUM LIKELIHOOD ESTIMATION USING EXPONENTIAL FAMILIES (Iván Díaz and Michael Rosenblum) Johns Hopkins University, Dept. of Biostatistics Working Papers (2014)

Targeted maximum likelihood estimation (TMLE) is a general method for estimating parameters in semiparametric and nonparametric models. Each iteration of TMLE involves fitting a parametric submodel that targets the parameter of interest. We investigate the ...

Clinic Design, Key Practice Metrics, and Resident Satisfaction in Internal Medicine Continuity Clinics: Findings of the Educational Innovations Project Ambulatory Collaborative (Michael Rosenblum) All Scholarly Works (2014)

Background Internal medicine programs are redesigning ambulatory training to improve the resident experience and answer the challenges of conflicting clinical responsibilities. However, little is known about the effect of clinic redesign on residents' satisfaction. Objective ...

Training the ambulatory internist: rebalancing residency education (Gina Luciano, Michael Rosenblum and Sudeep Kaur Aulakh) All Scholarly Works (2014)

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ADAPTIVE RANDOMIZED TRIAL DESIGNS THAT CANNOT BE DOMINATED BY ANY STANDARD DESIGN AT THE SAME TOTAL SAMPLE SIZE (Michael Rosenblum) Johns Hopkins University, Dept. of Biostatistics Working Papers (2014)

Prior work has shown that certain types of adaptive designs can always be dominated by a suitably chosen, standard, group sequential design. This applies to adaptive designs with rules for modifying the total sample size. ...

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Estimating population treatment effects from a survey sub-sample (Kara E Rudolph, Ivan Diaz, Michael Rosenblum, et al.) Estimating populaton treatment effects from a survey subsample (2014)

We consider the problem of estimating an average treatment effect for a target population from a survey sub-sample. Our motivating example is generalizing a treatment effect estimated in a sub-sample of the National Comorbidity Survey ...

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UNIFORMLY MOST POWERFUL TESTS FOR SIMULTANEOUSLY DETECTING A TREATMENT EFFECT IN THE OVERALL POPULATION AND AT LEAST ONE SUBPOPULATION (Michael Rosenblum) Johns Hopkins University, Dept. of Biostatistics Working Papers (2013)

After conducting a randomized trial, it is often of interest to determine treatment effects in the overall study population, as well as in certain subpopulations. These subpopulations could be defined by a risk factor or ...

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TRIAL DESIGNS THAT SIMULTANEOUSLY OPTIMIZE THE POPULATION ENROLLED AND THE TREATMENT ALLOCATION PROBABILITIES (Brandon S. Luber, Michael Rosenblum and Antoine Chambaz) Johns Hopkins University, Dept. of Biostatistics Working Papers (2013)

Standard randomized trials may have lower than desired power when the treatment effect is only strong in certain subpopulations. This may occur, for example, in populations with varying disease severities or when subpopulations carry distinct ...

Transforming primary care training-patient-centered medical home entrustable professional activities for internal medicine residents (Michael Rosenblum) All Scholarly Works (2013)

INTRODUCTION: The U.S. faces a critical gap between residency training and clinical practice that affects the recruitment and preparation of internal medicine residents for primary care careers. The patient-centered medical home (PCMH) represents a new ...

About Michael Rosenblum MD

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clinical trials (1)

HIV prevention (1)

causal methods (1)

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