INTERADAPT -- AN INTERACTIVE TOOL FOR DESIGNING AND EVALUATING RANDOMIZED TRIALS WITH ADAPTIVE ENROLLMENT CRITERIAJohns Hopkins University, Dept. of Biostatistics Working Papers
Date of this Version6-14-2014
AbstractThe interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer tangible benefits compared to standard designs, in the context of investigators’ specific trial goals and constraints. Specifically, interAdapt compares the performance of trial designs with adaptive enrollment criteria versus standard (non-adaptive) group sequential trial designs. Performance is compared in terms of power, expected trial duration, and expected sample size. Users can either work directly in the R console, or with a user-friendly shiny application that requires no programming experience. Several added features are available when using the shiny application. For example, the application allows users to immediately download the results of the performance comparison as a csv-table, or as a printable, html-based report.
Citation InformationAaron Joel Fisher, Harris Jaffee and Michael Rosenblum. "INTERADAPT -- AN INTERACTIVE TOOL FOR DESIGNING AND EVALUATING RANDOMIZED TRIALS WITH ADAPTIVE ENROLLMENT CRITERIA" (2014)
Available at: http://works.bepress.com/michael_rosenblum/55/