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About Kim N. Ha, Ph.D.

My laboratory is interested in correlating structure-dynamics-function relationships in proteins utilizing an array of biochemical techniques and solution-state NMR spectroscopy. I have extensive expertise in the study of mutations of the cardiac membrane protein phospholamban (PLN), and the adipocyte lipid chaperone fatty acid binding protein 4 (FABP4). Students in my laboratory develop practical skills in recombinant protein expression, isolation, and characterization.

Positions

2012 - Present Associate Professor, St. Catherine University Department of Chemistry and Biochemistry
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Grants

2018 - Present Structural Basis of Dilated Cardiomyopathy
National Heart Lung and Blood Institute - 5R01HL144130
Role: Collaborator
2019 - 2020 Measuring the structural dynamics of Hox family transcription factor lin-39 and its mutant lin-39(ccc16) in complex with mab-5 and DNA using NMR spectroscopy.
Summer Scholars Program
Role: Co-PI
Colleague(s): Dr. Andrea Kalis, Biology
2019 - 2019 Hox protein function in patterning C. elegans neuronal cell fates
Small 3M Collaborative Research Grant
Role: Co-PI
Colleague(s): Dr. Andrea Kalis, Biology
2018 - 2019 Determining the Impact of Domain Ib Mutations of Phospholamban on Phosphorylation and SERCA Regulation
Summer Scholars Program
Role: PI
2017 - 2018 Characterizing Dynamics-Driven Ligand Selection of Adipocyte Fatty Acid Binding Protein
APDC Faculty Scholarship Award
Role: PI
2016 - 2017 Characterization of Dilated Cardiomyopathy Linked R25 Mutations of Phospholamban
Clare Boothe Luce Collaborative Research Award
Role: PI
2012 - 2016 Phase Forward: Turning Obstacles into Opportunities
National Science Foundation S-STEM Program
Role: Co-PI
2015 - 2015 Console upgrade of 600 MHz NMR Spectrometer
Office of the Director, National Institutes of Health
Shared Instrumentation Grant
Role: Co-PI
2014 - 2015 NMR Resonance Assignment of Fatty Acid Binding Protein-4
Summer Scholars Program
Role: PI
2014 - 2015 Pushing the limits of rational design in therapeutic phospholamban mutants through optimizing dephosphorylation by protein-phosphatase 1
Large 3M Collaborative Research Grant
Role: PI
2013 - 2014 Dephosphorylation on Therapeutic Mutants of the Cardiac Protein Phospholamban
Clare Booth Luce Collaborative Research Award
Role: PI
2009 - 2012 Rational Design of Loss-of-Function Phospholamban Mutants for Gene Therapy
National Heart Lung and Blood Institute - F31HL095361
Role: Fellow
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Professional Service and Affiliations

2017 - Present Member, Committee of Inclusion and Diversity, Biophysical Society
2012 - Present Vice President, Iota Sigma Pi Mercury Chapter
2018 - 2020 Co-chair, University Faculty Evaluation Promotion and Tenure Committee (UFEPT)
2017 - 2018 President, Midwest Association of Chemistry Teachers at Liberal Arts Colleges (MACTLAC)
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Honors and Awards

  • Minnesota Medical Foundation. (2012). Dr. Marvin and Hassedeh Bacaner Award for creativity in biomedical research
  • Department of Biochemistry, Molecular Biology, and Biophysics - University of Minnesota. (2011). Ross A. Gortner Award for excellence in protein chemistry and enzymology research.
  • Department of Biochemistry, Molecular Biology, and Biophysics - University of Minnesota. (2011). Beatrice Z. Milne and Theodore Brandenburg Award for Excellence in Graduate Thesis Research
  • Department of Biochemistry, Molecular Biology, and Biophysics - University of Minnesota. (2011). Cyrus Barnum Teaching Award
  • College of Biological Sciences - University of Minnesota. (2011). Teaching Assistant of the Year Award, Finalist
  • National Heart Lung and Blood Institute, NIH. (2008). Ruth Kirschstein National Research Service Award Predoctoral Fellowship
  • Department of Biochemistry, Molecular Biology, and Biophysics - University of Minnesota (2012). Armstrong Pothapragada Award in Biochemistry


Education

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2012 Ph.D., Biochemistry, University of Minnesota - Twin Cities
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2007 Master of Science, Chemistry, University of Minnesota - Twin Cities
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2004 Bachelor of Arts, Chemistry, University of Minnesota - Twin Cities
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Contact Information

St. Catherine University
2004 Randolph Avenue
St. Paul, MN 55105

651-690-8617

Email:


Poster Presentations (11)

Publications (9)

Conference Talks (1)

Conference Talks by Undergraduate Researchers (4)