Pediatric Nephrologist; Division Head, Nephrology
Dr. Guido Filler is nephrologist whose research largely concerns childhood kidney disorders, hypertension, population health, and nutrition at the hospital's Nephrology and Hypertension Clinic.
Children's Health Collaborators: Kambiz Norozi, Ram Singh, Ajay P. Sharma, Amrit Kirpalani, and Christopher McIntyre
Dr. Filler's research has grown from disease markers and therapies, including transplantation, to include renal function, preventative medicine, drug disposition in children, and health services research.
Dr. Filler is Professor of Paediatrics with cross-appointments in medicine and pathology & laboratory medicine. He served as Chair of the Department of Paediatrics at Western University and Chief of Paediatrics at the Children's Hospital, London Health Sciences Centre from 2006 to 2016. Born in Germany, Dr. Filler sought international experience early in his life and spent a year in Phoenix, Arizona, where he completed High School. He earned his undergraduate and medical degrees from Hannover Medical School in Germany and completed his speciality training in Paediatrics at the same institution. In 1988 he won a prestigious scholarship of the "Deutsche Forschungsgemeinschaft" - German equivalent to the CIHR - and spent two years of the subspecialty and research training at the Hospital for Sick Children at Great Ormond Street in London, UK.
After his return to Germany in 1990, he became a consult paediatric nephrologist and worked in Hannover and Berlin. He completed a PhD in clinical pharmacology at the Charité Hospital, Humboldt University at Berlin, and promoted to Associate Professor. In 1997, Dr. Filler became acting head of the Division of Paediatric Nephrology at the Charité, where he was able to serve as the principal investigator of the first published randomized controlled clinical trial in paediatric transplantation, comparing Cyclosporine Microemulsion and Tacrolimus. In 1999, Dr. Filler assumed the role as Chief of the Division of Nephrology at the Children's Hospital of Eastern Ontario (CHEO) in Ottawa and was promoted to Professor in 1999. He was also appointed to the Department of Pathology and Laboratory Medicine.
Dr. Filler developed the paediatric nephrology unit in Ottawa and established together with Dr. Hutchison, a paediatric continuous renal replacement program at CHEO. He also established a new, superior method for the measurement of renal function in children using a single blood test and the measurement of Cystatin C, a low molecular weight protein. In 2006, he became Chair of the Department of Paediatrics, University of Western Ontario and Paediatrician in Chief. He was renewed for a second term in 2011.
Dr. Filler has authored over 300 peer-reviewed publications and is an active participant in a large array of administrative committees within this academic health sciences centre. Apart from his nephrological research (especially cardiorenal syndrome type IV and improving outcomes of children with CKD), he focused on the optimization of paediatric drug dosing by studying pharmacokinetic/pharmacodynamic relationships of various drugs in children. Another major field of research is population health and paediatrician workforce based. He is the deputy editor of the journal "Pediatric Transplantation" and "Pediatric Nephrology" and he is on the editorial board of paediatric nephrology, transplantation, pharmacology and paediatric journals. He has also been recognized for his postgraduate teaching.
Research Interest Area: Kidney disorders
Research Overview: Outogeny of drug disposition; Measurement of renal function; Obesity; Clinical nephrology; Protein biochemistry
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About Guido Filler
Dr. Guido Filler is nephrologist whose research largely concerns childhood kidney disorders, hypertension, population health, and nutrition at the hospital's Nephrology and Hypertension Clinic.
Children's Health Collaborators: Kambiz Norozi, Ram Singh, Ajay P. Sharma, Amrit Kirpalani, and Christopher McIntyre
Dr. Filler's research has grown from disease markers and therapies, including transplantation, to include renal function, preventative medicine, drug disposition in children, and health services research.
Dr. Filler is Professor of Paediatrics with cross-appointments in medicine and pathology & laboratory medicine. He served as Chair of the Department of Paediatrics at Western University and Chief of Paediatrics at the Children's Hospital, London Health Sciences Centre from 2006 to 2016. Born in Germany, Dr. Filler sought international experience early in his life and spent a year in Phoenix, Arizona, where he completed High School. He earned his undergraduate and medical degrees from Hannover Medical School in Germany and completed his speciality training in Paediatrics at the same institution. In 1988 he won a prestigious scholarship of the "Deutsche Forschungsgemeinschaft" - German equivalent to the CIHR - and spent two years of the subspecialty and research training at the Hospital for Sick Children at Great Ormond Street in London, UK.
After his return to Germany in 1990, he became a consult paediatric nephrologist and worked in Hannover and Berlin. He completed a PhD in clinical pharmacology at the Charité Hospital, Humboldt University at Berlin, and promoted to Associate Professor. In 1997, Dr. Filler became acting head of the Division of Paediatric Nephrology at the Charité, where he was able to serve as the principal investigator of the first published randomized controlled clinical trial in paediatric transplantation, comparing Cyclosporine Microemulsion and Tacrolimus. In 1999, Dr. Filler assumed the role as Chief of the Division of Nephrology at the Children's Hospital of Eastern Ontario (CHEO) in Ottawa and was promoted to Professor in 1999. He was also appointed to the Department of Pathology and Laboratory Medicine.
Dr. Filler developed the paediatric nephrology unit in Ottawa and established together with Dr. Hutchison, a paediatric continuous renal replacement program at CHEO. He also established a new, superior method for the measurement of renal function in children using a single blood test and the measurement of Cystatin C, a low molecular weight protein. In 2006, he became Chair of the Department of Paediatrics, University of Western Ontario and Paediatrician in Chief. He was renewed for a second term in 2011.
Dr. Filler has authored over 300 peer-reviewed publications and is an active participant in a large array of administrative committees within this academic health sciences centre. Apart from his nephrological research (especially cardiorenal syndrome type IV and improving outcomes of children with CKD), he focused on the optimization of paediatric drug dosing by studying pharmacokinetic/pharmacodynamic relationships of various drugs in children. Another major field of research is population health and paediatrician workforce based. He is the deputy editor of the journal "Pediatric Transplantation" and "Pediatric Nephrology" and he is on the editorial board of paediatric nephrology, transplantation, pharmacology and paediatric journals. He has also been recognized for his postgraduate teaching.
Research Interest Area: Kidney disorders
Research Overview: Outogeny of drug disposition; Measurement of renal function; Obesity; Clinical nephrology; Protein biochemistry
| Present | Division Chief, Paediatric Nephrology, London Health Sciences Centre ‐ Children's Hospital | |
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| Present | Division Head, Nephrology; Professor, Western University ‐ Department of Paediatrics | |
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| Present | Professor, Western University ‐ Department of Pathology and Laboratory Medicine | |
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| Present | Professor, Western University ‐ Department of Medicine | |
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| Present | Scientist, Lawson Health Research Institute ‐ Children's Health Research Institute (CHRI) | |
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