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About Brian J. Balin

Dr. Balin is a professor in the department of Biomedical Sciences, teaching in both the DO and Biomedical masters programs. He lectures and participates in case presentations and laboratory sessions on a variety of subjects including: neuroscience, neuroanatomy, neurodegeneration, neuropathology, general pathology, molecular basis of cancer, and infectious disease.

Dr. Balin is an internationally-recognized expert in the field of Alzheimer's Disease research. He is highly published in peer-reviewed journals, and has written a number of chapters and reviews on the pathology of Alzheimer's disease, including reviews on the "Pathogen Hypothesis" of this disease (see live discussion section, In addition, he has presented and continues to present his work at major national and international scientific meetings including a number of international and world congresses on Alzheimer's disease and related dementias.


Present Chair, Philadelphia College of Osteopathic Medicine Department of Bio-Medical Sciences
Present Director of Basic Science Research, Center for Chronic Disorders of Aging
Present Professor of Neuroscience and Neuropathology, Philadelphia College of Osteopathic Medicine Department of Bio-Medical Sciences


2006 - Present Endowment for the Center for Chronic Disorders of Aging
Osteopathic Heritage Foundation Endowment
Role: PI (Director, CCDA)
2003 - Present The role of Chlamydia pneumoniae in the pathogenesis of sporadic Alzheimer’s disease
Adolf and Rose Levis Foundation
Role: PI
2011 - 2011 The case for an infectious etiology of late onset Alzheimer’s disease
IHVR (Institute for Hepatitis and Virus Research) through a DCED (Department of Community and Economic Development) Innovation Grant from the State of Pennsylvania
Talent Scout for Technology
Role: PI
2004 - 2007 Chlamydia pneumoniae infection of mice triggers Alzheimer-like pathology
IIRG – Alzheimer’s Association
Role: PI
1999 - 2004 Chlamydia pneumoniae: a pathogen in Alzheimer’s Disease?
NIH/NIAID - R01- AI44055-01A1
Role: Co-PI
2000 - 2002 Immunosenescence and Chlamydia Pneumoniae
NIH/ R15
Role: Co-Investigator
1992 - 1997 The neuronal cytoskeleton in aging and Alzheimer's Disease
NIH/NIA - R29-AG10160
Role: PI
1995 - 1996 Differential expression and sorting of the neuron-specific class III b-tubulin isotype in human neuronal and neuroendocrine tumor cell lines maintained in an organ culture system
AHERF Neurosciences Grant - G9410-020-Y01
Role: Co-PI
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Professional Service and Affiliations

1999 - 2011 Member, Admissions Committee for Philadelphia College of Osteopathic Medicine
2009 - 2010 Faculty Representative to Executive Faculty, PCOM
2008 - 2009 Chair, Faculty Senate – PCOM
2004 - 2008 Member, Academic Planning and Budget Committee for PCOM
1999 - 2003 Chairman, IACUC for Philadelphia College of Osteopathic Medicine
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Honors and Awards

  • Medical College of Pennsylvania Nominee for Presidential Faculty Fellowship Program (1992)
  • Amer Soc for Cell Biology-Glenn Foundation Award for Outstanding Research in Aging (1996)
  • Professor of the Year 2008 – Philadelphia College of Osteopathic Medicine – Awarded by DO class of 2010
  • Alzheimer’s Association “Making the Difference” – in recognition of co-editorship of JAOA Supplement – “Managing Alzheimer’s disease through early detection and treatment - 2010


PhD, University of Maryland School of Medicine
BS, University of Maryland

Contact Information

P: 215-871-6862


Scholarly Articles (57)