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Article
Role of Microbes in the Development of Alzheimer's Disease: State of the Art - An International Symposium Presented at the 2017 IAGG Congress in San Francisco.
Frontiers in Genetics
  • Tamàs Fülöp
  • Ruth F Itzhaki
  • Brian J. Balin, PhD, Philadelphia College of Osteopathic Medicine
  • Judith Miklossy
  • Annelise E Barron
Document Type
Article
Publication Date
1-1-2018
Abstract

This article reviews research results and ideas presented at a special symposium at the International Association of Gerontology and Geriatrics (IAGG) Congress held in July 2017 in San Francisco. Five researchers presented their results related to infection and Alzheimer's disease (AD). Prof. Itzhaki presented her work on the role of viruses, specifically HSV-1, in the pathogenesis of AD. She maintains that although it is true that most people harbor HSV-1 infection, either latent or active, nonetheless aspects of herpes infection can play a role in the pathogenesis of AD, based on extensive experimental evidence from AD brains and infected cell cultures. Dr. Miklossy presented research on the high prevalence of bacterial infections that correlate with AD, specifically spirochete infections, which have been known for a century to be a significant cause of dementia (e.g., in syphilis). She demonstrated how spirochetes drive senile plaque formation, which are in fact biofilms. Prof. Balin then described the involvement of brain tissue infection by the

PubMed ID
30250480
Comments

This article was published in Frontiers in Genetics, Volume 9.

The published version is available at https://doi.org/10.3389/fgene.2018.00362.

Copyright © 2018 Fülöp, Itzhaki, Balin, Miklossy and Barron. CC BY 4.0.

Citation Information
Tamàs Fülöp, Ruth F Itzhaki, Brian J. Balin, Judith Miklossy, et al.. "Role of Microbes in the Development of Alzheimer's Disease: State of the Art - An International Symposium Presented at the 2017 IAGG Congress in San Francisco." Frontiers in Genetics Vol. 9 (2018)
Available at: http://works.bepress.com/brian_balin/77/