Dr. Braun is currently focused on understanding how exercise, dietary
energy/composition and/or pharmacological agents interact to mediate insulin resistance
and the risk for Type-2 diabetes. The American Diabetes Association is our major source
of funding for work on how the combination of exercise and/or the drug metformin impact
glucose metabolism and insulin sensitivity at the cellular and whole-body levels. We also
use stable isotope tracers to measure the regulation of substrate kinetics during
exercise. Recent studies include the effects of concurrent energy surplus and exercise on
insulin sensitivity, the net impact of high body fat and high cardiorespiratory fitness
in women, and the utility of alternative carbohydrates to maintain optimal blood glucose
control in humans with Type-2 diabetes. 

Articles

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Independent and Combined Effects of Exercise Training andMetformin on Insulin Sensitivity in Individuals With Prediabetes (with Steven K. Malin, Robert Gerber, and Stuart R. Chipkin), Diabetes Care (2012)

OBJECTIVE Physical activity or metformin enhances insulin sensitivity and opposes the progression from prediabetes to...

 

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Feasibility and Efficacy of a Physical Activity Intervention Among Pregnant Women: The Behaviors Affecting Baby and You (B.A.B.Y.) Study (with Lisa Chasan-Taber, Marushka Silveira, Bess H. Marcus, Edward Stanek, and Glenn Markenson), Journal of Physical Activity and Health (2011)

Background: Physical activity during pregnancy is associated with reduced risk of adverse maternal and fetal...

 

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The effect of carbohydrate availability following exercise on whole body insulin action (with Elizabeth Mitchell, Patty S. Freedson, and Stuart R. Chipkin), Applied Physiology, Nutrition, and Metabolism (2008)

One bout of exercise enhances insulin-stimulated glucose uptake (insulin action), but the effect is blunted...

 

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Impact of metformin on peak aerobic capacity, Applied Physiology, Nutrition, and Metabolism (2008)

Individually, exercise and the drug metformin have been shown to prevent or delay type 2...

 

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Effect of timing of energy/carbohydrate replacement on post-exercise insulin action, Applied Physiology, Nutrition, and Metabolism (2007)

The nutritional environment surrounding an exercise bout modulates post-exercise insulin action. The purpose of this...