Professor, Biochemistry and Microbiology
Dr. Susan H. Jackman is a Professor for Biochemistry and Microbiology.
Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
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Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
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About Susan H. Jackman
Dr. Susan H. Jackman is a Professor for Biochemistry and Microbiology.
Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
| Present | Professor, Biochemistry and Microbiology, Marshall University | |
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Disciplines
Biochemistry, Cell Biology, Other Cell and Developmental Biology, Microbiology, Bacteriology, Physiology, Cellular and Molecular Physiology, Cells, Bacterial Infections and Mycoses, Immune System Diseases, Skin and Connective Tissue Diseases, Biological Phenomena, Cell Phenomena, and Immunity, Digestive, Oral, and Skin Physiology, Medical Biochemistry, Medical Cell Biology, Medical Immunology, Medical Microbiology, Medical Physiology, Physiological Processes, and Bacteria
Research Interests
Honors and Awards
- Certificate of Teaching Excellence, Joan C Edwards School of Medicine, 2009
- Association of American Medical Colleges’ Medical Education Research Certificate
Links
Contact Information
Phone: 304-696-7342
Fax: 304-696-7207
Email: