|Present||Professor of Biochemistry, Biophysics and Molecular Biology, Iowa State University|
Combining Disparate Data Types: Protein Sequences and Protein Structures
Journal of Data Mining in Genomics & Proteomics (2015)
With the development of high-throughput, next-generation sequencing and other advanced technologies, a large number of gene expression profiles have been ...
Conformational Analysis of Receptor Selective Tachykinin Analogs: Senktide and Septide
Journal of Biomolecular Structure and Dynamics (2012)
The conformational behavior in solution of two receptor selective tachykinin agonists, senktide (succiny1-D-F-MeF-G-L-M-NH2) and septide (pQ-F-F-P-L-M-NH2) is described. Two dimensional ...
How noise in force fields can affect the structural refinement ...
Proteins: Structure, Function, and Bioinformatics (2012)
Structural refinement of predicted models of biological macromolecules using atomistic or coarse-grained molecular force fields having various degree of error ...
MultiBody Coarse-Grained Potentials for Native Structure Recognition and Quality Assessment ...
Proteins: Structure, Function, and Bioinformatics (2011)
Multi-body potentials have been of much interest recently because they take into account three dimensional interactions related to residue packing ...
Analysis of protein dynamics using local-DME calculations
International Journal of Bioinformatics Research and Applications (2011)
Flexibility and dynamics of protein structures are reflected in the B-factors and order parameters obtained experimentally with X-ray crystallography and ...