Sciatica is a common chief complaint addressed by medical professionals in today's society and can prove to be extremely debilitating if left untreated. The musculoskeletal changes seen in pregnancy can often lead to an exacerbation or recurrence of this condition. Osteopathic manipulative treatment (OMT) can provide an additional method of managing these symptoms by treating somatic dysfunctions that persist into the postpartum period. A 28-year-old female three months postpartum was seen in our clinic for recurrent right hip pain, right-sided sciatica and chronic headaches. Using osteopathic manipulative techniques, the patient's somatic dysfunctions were removed and her symptoms immediately resolved post-treatment. Although initially successful, the patient returned to the clinic 11 days later reporting a recurrence of her symptoms and was again treated with osteopathic manipulative treatment. This case study examines the persistence of somatic dysfunction into the postpartum period and the benefits of taking an osteopathic manipulative approach toward resolving the symptoms of sciatica in this specific population.