My lab studies plasticity in the sensory system, particularly of the sensory neurons that innervate skeletal muscle. Muscles have many sensory neurons that constantly monitor muscle stretch, tension, temperature, pH, pain, and more. Improper activation of these sensory neurons can lead to pathologies like chronic pain or impaired balance and movement. To study muscle sensory neurons we use an isolated mouse muscle nerve preparation where we can directly record changes in sensory nerve firing properties in response to disease states, drugs, or a variety of other perturbations.