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P-33 Development of a novel biosensor setup of combined QCM-D and FET
Celebration of Research and Creative Scholarship
  • Hyun J. Kwon, Andrews University
  • Ricardo Huancaya, Andrews University
  • Thomas Zirkle, Andrews University
Presenter Status
Department of Engineering and Computer Science
Second Presenter Status
Undergraduate Student, Department of Engineering and Computer Science
Third Presenter Status
Undergraduate Student, Department of Engineering and Computer Science
Location
Buller Hallway
Start Date
8-11-2012 3:00 PM
End Date
8-11-2012 5:00 PM
Presentation Abstract

A novel setup of a biosensor that combines an EGFET (extended gate field effect transistor) and a QCM-D (quartz crystal microbalance with dissipation) has been developed. The setup utilized a commercial, affordable MOSFET, hard wired to the QCM-D without having to undergo complicated nanofabrication procedures. This sensor was capable of detecting changes in electrochemical and thickness/flexibility during bio-molecular interactions. For the proof of concept, DNA fragments of H1N1 were detected in the setup. The sensor demonstrated in situ, label-free, and multi-modal characterization of bio-molecular interactions with high sensitivity and multiple parameters through a simple instrumentation.

Citation Information
Hyun J. Kwon, Ricardo Huancaya and Thomas Zirkle. "P-33 Development of a novel biosensor setup of combined QCM-D and FET" (2012)
Available at: http://works.bepress.com/hyun_kwon/8/