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About Gregory Kelly

Dr. Greg Kelly is a molecular geneticist studying the relationship between cell-to-cell communication and development, to understand how those communication mechanisms can malfunction and lead to developmental delays and health defects later in life.

Children's Health Collaborators: Tom Drysdale and Katherine Willmore

Much of Dr. Kelly’s work focuses on the cell signalling “crosstalk” between Wnt and Hh genes, known to be a fundamental part of embryonic, neonatal, and adult development.

Why do cells become extraembryonic? Projects regarding cell signalling crosstalk and development of extraembryonic tissue, crucial for embryonic development. Using CRISPR technology and animal models, notably zebrafish and mouse.
Goal: to better understand the root of developmental delays and spontaneous abortion in early stages of pregnancy.

How does Wnt and Hh signalling influence development and disease? Looking into how specific cell differentiation is regulated by signalling, while evaluating the role of metabolism and epigenetics in the regulations of cell fate and development.
Goal: to understand what goes right – and therefore, wrong – during cell development.


Present Associate Scientist, Lawson Health Research Institute ‐ Children's Health Research Institute (CHRI)
Present Professor, Western University Department of Biology


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