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Graham Moran
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Loyola University Chicago
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Department of Chemistry and Biochemistry
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Featured Works
Recent Works
Featured Works
(1)
Article
The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer ...
American Chemical Society (2021)
Graham R. Moran
Dihydropyrimidine dehydrogenase (DPD) is a complex enzyme that reduces the 5,6-vinylic bond of pyrimidines, uracil, and thymine. 5-Fluorouracil (5FU) is ...
Link
Recent Works
(5)
Article
Finding Ways to Relax: A Revisionistic Analysis of the Chemistry ...
Finding Ways to Relax: A Revisionistic Analysis of the Chemistry of E. coli GTP Cyclohydrolase II. (2021)
Graham R. Moran
Link
Article
Mammalian Dihydropyrimidine Dehydrogenase. Archives of Biochemistry and Biophysics
Mammalian Dihydropyrimidine Dehydrogenase. Archives of Biochemistry and Biophysics (2021)
Graham R. Moran
Link
Article
Perturbing the Movement of Hydrogens to Delineate and Assign Events ...
Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase (2021)
Graham R. Moran
Link
Article
Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes ...
ACS Chemical Biology 16(1) (2021)
Graham R. Moran
OpenURL
Article
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a ...
JACS (2021)
Graham R. Moran
Link