Organizations increasingly emphasize the use of information technology in the procurement process. An integrative model of e-procurement adoption that captures its antecedents, two types of e-procurement use, and their respective effects on relationship development and perceived efficiency gains are proposed and empirically tested using the data collected from senior managers in four technology-intensive industries. Our findings indicate that the use of coordination e-procurement applications has both direct and indirect effects on perceived efficiency gains, while transactional application use can directly lead to efficiency gains. In addition, the use of e-procurement applications is strongly influenced by organizational learning ability and normative pressures. The findings provide a new perspective for managers in their future implementation of e-procurement applications.