SelectedWorks - Donald F. Smee

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Selected Works of Donald F. Smee

Emeritus Research Professor

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About Donald F. Smee

Present	Emeritus Research Professor, Utah State University ‐ Animal, Dairy and Veterinary Sciences
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Animal Sciences

American Society of Microbiology, Member
International Society for Antiviral Research, Member
Member, Editorial Board for Antiviral Research
Member, Publications Committee, International Society for Antiviral Research
Ad hoc reviewer for Journal of Medicinal Chemistry, Antiviral Chemistry and Chemotherapy and Antimicrobial Agents and Chemotherapy

Mail address:
Utah State University
5600 Old Main Hill
Logan, UT 84322-5600
Location:
Veterinary Science Building, Room 301
Office Phone:
(435) 797-2897
Fax:
(435) 797-3959

Email:

Articles (80)

A Molecularly Engineered Antiviral Banana Lectin Inhibits Fusion and is ...

National Academy of Sciences. Proceedings (2020)

Evelyn M. Covés-Datson, Steven R. King, Maureen Legendre, Auroni Gupta, et al.

There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. ...

Combinations of favipiravir and peramivir for the treatment of pandemic ...

Antiviral Research (2012)

E B Tarbet, M Maekawa, Y Furuta, Y S Babu, et al.

Favipiravir, an influenza virus RNA polymerase inhibitor, and peramivir, an influenza virus neuraminidase inhibitor, were evaluated alone and in combination ...

Use of Plethysmography in Assessing the Efficacy of Antivirals in ...

Antiviral Research (2011)

Justin G. Julander, J. Hagloch, S. Latimer, N. Motter, et al.

The recently emerged swine-origin H1N1 influenza A virus (IAV) caused a pandemic outbreak in 2009 with higher risk of severe ...

T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

Antimicrobial Agents and Chemotherapy (2011)

Michelle Mendenhall, Andrew Russell, Terry Juelich, Emily L. Messina, et al.

A number of New World arenaviruses (Junin [JUNV], Machupo [MACV], and Guanarito [GTOV] viruses) can cause human disease ranging from ...

Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of ...

PLoS Neglected Tropical Diseases (2011)

M. Mendenhall, A. Russell, Donald F. Smee, Jeffery O. Hall, et al.

Background Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic ...

In vitro and in vivoefficacy of fluorodeoxycytidine analogs against highly ...

In vitro and in vivoefficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1,seasonal, and pandemic H1N1 virus infections (2011)

Y. Kumaki, C. W. Day, Donald F. Smee, John D. Morrey, et al.

Various fluorodeoxyribonucleosides were evaluated for their antiviral activities against influenza virus infections in vitro and in vivo. Among the most ...

Inhibition ofsevere acute respiratory syndrome coronavirus replication in a lethal ...

Inhibition ofsevere acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/cmouse model by stinging nettle lectin, Urtica dioica agglutinin (2011)

Y. Kumaki, M. K. Wandersee, A. J. Smith, Y. Zhou, et al.

Urtica dioica agglutinin (UDA) is a small plant monomeric lectin, 8.7 kDa in size, with an N-acetylglucosamine specificity that inhibits ...

Maporal virus as asurrogate for pathogenic New World hantaviruses and ...

Antiviral Chemistry & Chemotherapy (2011)

K. K. Buys, K. H. Jung, Donald F. Smee, Y. Furuta, et al.

Background: Pathogenic hantaviruses geographically distributed in the Old World cause haemorrhagic fever with renal syndrome (HFRS), whereas New World hantaviruses ...

T-705(Favipiravir) inhibition of arenavirus replication in cell culture

Antimicrobial Agents and Chemotherapy (2011)

M. Mendenhall, A. Russell, T. Juelich, E. L. Messina, et al.

A number of New World arenaviruses (Junín [JUNV], Machupo [MACV], and Guanarito [GTOV] viruses) can cause human disease ranging from ...

(–)-Carbodine: Enantiomeric Synthesis and in Vitro Antiviral Activity Against Various ...

Carbodine: enantiomeric synthesis and in vitro antiviral activity againstvarious strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1(swine flu) (2010)

J. R. Rao, A. K. Jha, R. K. Rawal, A. Sharon, et al.

Enantiomerically pure cyclopentyl cytosine [(−)-carbodine 1] was synthesized from d-ribose and evaluated for its anti-influenza activity in vitro in comparison ...

Combinations of Oseltamivir and Peramivir for the Treatment of Influenza ...

Antiviral Res (2010)

Donald F. Smee, B L Hurst, M H Wong, E B Tarbet, et al.

Oseltamivir and peramivir are being considered for combination treatment of serious influenza virus infections in humans. Both compounds are influenza ...

Development of a new Tacaribearenavirus infection model and its use ...

PLoS ONE (2010)

Brian B. Gowen, M. H. Wong, D. Larson, W. Ye, et al.

Background A growing number of arenaviruses can cause a devastating viral hemorrhagic fever (VHF) syndrome. They pose a public health ...

Effects of the combination of favipiravir (T-705) and oseltamivir on ...

Antimicrob Agents Chemother (2010)

Donald F. Smee, B L Hurst, M H Wong, K W Bailey, et al.

Favipiravir (T-705 [6-fluoro-3-hydroxy-2-pyrazinecarboxamide]) and oseltamivir were combined to treat influenza virus A/NWS/33 (H1N1), A/Victoria/3/75 (H3N2), and A/Duck/MN/1525/81 (H5N1) infections. T-705 ...

Efficacy of 2'-C-methylcytidine against yellow fever virus in cell ...

Antiviral Res (2010)

Justin G. Julander, A K Jha, J A Choi, K H Jung, et al.

Yellow fever virus (YFV) continues to cause outbreaks of disease in endemic areas where vaccine is underutilized. Due to the ...

Efficacy of Favipiravir (T-705) and T-1106 Pyrazine Derivatives in Phlebovirus ...

Antiviral Research (2010)

Brian B. Gowen, M. H. Wong, K. H. Jung, Donald F. Smee, et al.

Several studies have reported favipiravir (T-705) to be effective in treating a number of viral diseases modeled in rodent systems. ...

PSI-7851, a Pronucleotide of β-D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine Monophosphate ...

Antimicrob Agents Chemother (2010)

A M Lam, E Murakami, C Espiritu, H M Steuer, et al.

The hepatitis C virus (HCV) NS5B RNA polymerase facilitates the RNA synthesis step during the HCV replication cycle. Nucleoside analogs ...

A new mouse-adapted strain of SARS-CoV as a lethal model ...

Virology (2009)

C. W. Day, R. Baric, S. X. Cai, M. Frieman, et al.

Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New lethal animal models for ...

A recombinant,infectious human parainfluenza virus type 3 expressing the ...

A recombinant,infectious human parainfluenza virus type 3 expressing the enhanced green fluorescentprotein for use in high-throughput antiviral assays (2009)

J. P. Roth, J. K. Li, Donald F. Smee, John D. Morrey, et al.

The ability to rescue an infectious, recombinant, negative-stranded, RNA virus from a cDNA clone, has led to new opportunities for ...

Activity of T-705 in a Hamster Model of Yellow Fever ...

Antimicrob Agents Chemother (2009)

Justin G. Julander, K Shafer, Donald F. Smee, John D Morrey, et al.

Treatment with the nucleoside analog T-1106 was previously shown to be effective in a hamster model of yellow fever virus ...

Effect of T-705 Treatment on Western Equine Encephalitis in a ...

Antiviral Res (2009)

Justin G. Julander, Donald F. Smee, John D Morrey and Yousuke Furuta

A mouse model of western equine encephalitis (WEE) was characterized for use in antiviral studies. Virus was detected in several ...

Effects of Combinations of Favipiravir (T-705) and Oseltamivir on Influenza ...

Antimicrob Agents Chemother (2009)

Donald F. Smee, B L Hurst, M H Wong, K W Bailey, et al.

Effects of double combinations of amantadine, oseltamivir, and ribavirin on ...

Antimicrob Agents Chemother (2009)

Donald F. Smee, B L Hurst, M H Wong, K W Bailey, et al.

An amantadine-resistant influenza A/Duck/MN/1525/81 (H5N1) virus was developed from the low-pathogenic North American wild-type (amantadine-sensitive) virus for studying treatment of ...

T-705 (favipiravir) and related compounds: Novelbroad-spectrum inhibitors of RNA viral ...

T-705 (favipiravir) and related compounds: Novelbroad-spectrum inhibitors of RNA viral infections (2009)

Y. Furuta, K. Takahashi, K. Shiraki, K. Sakamoto, et al.

A series of pyrazinecarboxamide derivatives T-705 (favipiravir), T-1105 and T-1106 were discovered to be candidate antiviral drugs. These compounds have ...

Antiviral activities andphosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells ...

Antiviral activities andphosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infectedwith vaccinia virus (2008)

Donald F. Smee, D. E. Humphreys, B. L. Hurst and Dale L. Barnard

The Antipoxviral activities and phosphorylation of N-methanocarbathymidine ([N]-MCT) and four 5-halo-2'-deoxyuridines, namely 5-flouro- (FdU), 5-chloro- (CldU), 5-bromo- (BrdU), and 5-iodo- ...

C3H/HeN mouse model for the evaluation of antiviral agents ...

Antiviral Res (2008)

Justin G. Julander, Ramona T. Skirpstunas, V Siddharthan, K Shafer, et al.

The TC-83 vaccine strain of Venezuelan equine encephalitis virus (VEEV) causes encephalitis and death in C3H/HeN mice infected by intranasal ...