Professor of Pharmacology
After completing his PhD in genetics at the Pennsylvania State University, Dr. Peffley did postdoctoral training in molecular biology at the University of Colorado School of Medicine in Denver, Colorado. His first faculty position was in the Department of Pharmacology at the University of Tennessee Health Sciences Center in Memphis, Tennessee. At this institution, Dr. Peffley obtained his first NIH grant that focused on cholesterol synthesis.
Dr. Peffley then moved to the Rosalind Franklin School of Medicine in North Chicago, Illinois where he was promoted to associate professor in the Department of Pharmacology and Molecular Biology. His research interests moved from cholesterol research to the dietary prevention of cancer. To support this research, Dr. Peffley received an NIH grant from the National Cancer Institute.
A promotion to full professor lead Dr. Peffley to the Kansas City University of Medicine and Bioscience in the Department of Pharmacology. At this institution he continued his research in dietary prevention of cancer as well as teaching pharmacology, genetics and biochemistry. While in Kansas City, Dr. Peffley finished his Juris Doctor in law at the University of Missouri Kansas City School of Law. He has also served as founding faculty at two medical schools including Edward Via College of Osteopathic Medicine and The University of South Carolina School of Medicine Greenville.
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About Dennis Peffley
After completing his PhD in genetics at the Pennsylvania State University, Dr. Peffley did postdoctoral training in molecular biology at the University of Colorado School of Medicine in Denver, Colorado. His first faculty position was in the Department of Pharmacology at the University of Tennessee Health Sciences Center in Memphis, Tennessee. At this institution, Dr. Peffley obtained his first NIH grant that focused on cholesterol synthesis.
Dr. Peffley then moved to the Rosalind Franklin School of Medicine in North Chicago, Illinois where he was promoted to associate professor in the Department of Pharmacology and Molecular Biology. His research interests moved from cholesterol research to the dietary prevention of cancer. To support this research, Dr. Peffley received an NIH grant from the National Cancer Institute.
A promotion to full professor lead Dr. Peffley to the Kansas City University of Medicine and Bioscience in the Department of Pharmacology. At this institution he continued his research in dietary prevention of cancer as well as teaching pharmacology, genetics and biochemistry. While in Kansas City, Dr. Peffley finished his Juris Doctor in law at the University of Missouri Kansas City School of Law. He has also served as founding faculty at two medical schools including Edward Via College of Osteopathic Medicine and The University of South Carolina School of Medicine Greenville.
| Present | Assistant Professor of Physiology and Pharmacology, Philadelphia College of Osteopathic Medicine ‐ Department of Bio-Medical Sciences | |
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Disciplines
Research Interests
Grants
| 1999 - 2006 | Modulation of Mevalonate Synthesis by Dietary Isoprenoids |
| National Cancer Institute - RO1 CA81756 | |
| Role: PI | |
| $621,566 | |
| 2003 - 2004 | Proteomic Analysis of Isoprenoid and Isoflavone-mediated Regulation of Cap-dependent and Cap-independent Protein Translation in Human Prostate Tumor Cells |
| Kansas City Area Life Sciences Institute Research Development Grant | |
| Role: PI | |
| $25,000 | |
| 1999 - 2000 | Cancer Prevention by Isoprenoid Constituents of Plants |
| National Cancer Institute - RO1 CA73418 | |
| Role: Co-Investigator | |
| $250,000 | |
| 1996 - 2000 | Regulation of 3 Hydroxy 3 methylglutaryl Coenzyme A Reductase by Mevalonate and Oxysterols |
| American Heart Association (National Chapter) - HL 44006-O4S1 | |
| Role: PI | |
| $120,000 | |
| 1996 - 1999 | Dietary Isoprenoid Regulation of Growth Related Genes |
| National Cancer Institute - R03 CA72527 | |
| Role: PI | |
| $50,000 | |
| 1990 - 1996 | Regulation of HMG-CoA Reductase in Mammalian Cells |
| National Heart, Lung and Blood Institute - RO1 HL44006 | |
| Role: PI | |
| $441,417 | |
| 1990 - 1993 | Regulation of HMG-CoA Reductase by Oxysterols and Mevalonate |
| American Heart Association (National Chapter) | |
| Role: PI | |
| $105,000 | |
| 1989 - 1990 | Regulation of HMG-CoA Reductase Gene Expression |
| American Health Assistance Foundation | |
| Role: PI | |
| $25,000 | |
| 1988 - 1990 | The Translational Control of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Mammalian Cells |
| American Heart Association – Tennessee Affiliate | |
| Role: PI | |
| $55,000 | |
| 1988 - 1989 | The Translational Control of HMG-CoA Reductase in Mammalian Cells |
| American Health Assistance Foundation | |
| Role: PI | |
| $25,000 |
Professional Service and Affiliations
| Member, American Association of Biochemistry and Molecular Biology | Member, American Bar Association | Member, American Society for Pharmacology and Experimental Therapeutics | Member, District of Columbia Bar Association | Member, Missouri Bar Association |
Honors and Awards
- Cora Louise Carson Award from the Tennessee Affiliate of the American Heart Association
- University of Health Sciences Research Support Award (2002)
- New Investigator Award - American Heart Association, Tennessee Affiliate
- UHS Faculty Publication Award (2002)
- 2nd Prize in the Nathan Burkan Memorial Competition (sponsored by the American Society of Composers, Authors and Publishers [ASCAP]) for paper entitled “Are Databases Adequately Protected by the 1976 Copyright Act in the Age of Bioinformatics?" (2003)
- University of Missouri-Kansas City School of Law: Dean’s Honor List: Fall Semester 2004
- Excellence Award in Molecular Medicine awarded at the Molecular Medicine: Applying Current and Emerging Technologies Conference, March 2008.
Courses
- Biochemistry
- Genetics
- Pharmacology
| BS, Juniata College ‐ Biology | ||
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| PhD, Pennsylvania State University ‐ Genetics | ||
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| JD, University of Missouri - Kansas City, School of Law | ||
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Links
Contact Information
T: 678-225-7575
Email: