"The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein." by Christopher Otis, MD

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Article

The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein.

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Christopher Otis, MD, Baystate Health
David Gang, MD, Baystate Health
Sadiqa Karim, MD, Baystate Health

Document Type

Article, Peer-reviewed

Publication Date

7-1-2006

Abstract

The absence of ganglion cells (GCs) is the primary anatomic abnormality in Hirschsprung disease. Light microscopy is the mainstay in establishing this diagnosis. However, establishing a condition of aganglionosis may be challenging on routine H&E-stai

Citation Information

Am J Clin Pathol. 2006 Jul;126(1):1-6.