"Mucoepidermoid carcinoma of the breast shares cytogenetic abnormality with mucoepidermoid carcinoma of the salivary gland: A case report with molecular analysis and review of the literature" by Christopher Otis, MD

Article

Mucoepidermoid carcinoma of the breast shares cytogenetic abnormality with mucoepidermoid carcinoma of the salivary gland: A case report with molecular analysis and review of the literature

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Christopher Otis, MD, Baystate Health
Sandra Camelo-Piragua, MD, Baystate Health
Claudine Habib, MD, Baystate Health
Prathima Kanumuri, MD, Baystate Health
Holly Mason, MD, Baystate Health

Document Type

Article, Peer-reviewed

Publication Date

6-1-2009

Abstract

Mucoepidermoid carcinoma of the breast is a rare entity with specific morphologic and immunohistochemical features similar to its salivary gland counterpart. In the 28 reported cases to date, there has not been a comparison of the molecular characteristics of this tumor with salivary gland mucoepidermoid carcinomas. Herein, a case of mucoepidermoid carcinoma of the breast with a molecular alteration similar to its salivary gland counterpart is reported. A lymph node metastasis was identified despite a predominantly in situ component and foci of microinvasion. The morphologic, immunohistochemical, prognostic, and molecular features are discussed.

Publication ISSN

0004-0010

Citation Information

Camelo-Piragua SI, Habib C, Kanumuri P, Lago CE, Mason HS, Otis CN. Mucoepidermoid carcinoma of the breast shares cytogenetic abnormality with mucoepidermoid carcinoma of the salivary gland: A case report with molecular analysis and review of the literature Hum Pathol 2009 Jun;40(6):887-92.