Assistant Professor, School of Pharmacy
Dr. Brian C. Train was born in Washington, D.C. in Georgetown Hospital and raised in Mechanicsburg, PA. He attended Washington & Jefferson College and received a B.A. in Biochemistry. During his training at W&J he was on the Dean’s List, swam and played water polo, and was an Academic All-American. After undergraduate training, Dr. Train enrolled in the Biomedical Sciences graduate program at West Virginia University in 2007.
In graduate school, Dr. Train investigated the conformational effects of arylhydrazine modified DNA adducts on DNA structure, specifically in relation to Z-DNA formation. His dissertation project required multi-stage synthesis of DNA adducts and DNA, which was then studied using Nuclear Magnetic Resonance spectroscopy (NMR), Circular Dichroism (CD), Liquid Chromatography-Mass Spectrometry (LC-MS), and Molecular Dynamics simulations (MD). Dr. Train’s project evaluated the potential implications of arylhydrazine carcinogenesis and Z-DNA biological significance. Upon completion of his dissertation, Single C8-Arylguanine Modified Hairpin Oligonucleotides: Synthesis, Conformational Analysis, and Tools for the Investigation of Z-DNA Formation, Dr. Train received a Ph.D. in Pharmaceutical and Pharmacological Sciences.
In addition while in graduate school, Dr. Train was an International Research Experience for Students (IRES) predoctoral fellow in 2009 where he worked at the State Key Laboratory of Supramolecular Structure and Materials at Jilin University in Changchun, Jilin, P.R. of China. He worked on a project to immobilize DNA on a gold film to quantify single strand binding protein (SSB) affinity for single-strand DNA using Single Molecule Force Microscopy (SMFS). He was also a Biochemistry tutor for the West Virginia University School of Pharmacy, which is how he found his passion for teaching. Dr. Train accepted an instructor position at Marshall University School of Pharmacy in August 2014.
Dr. Train is responsible to teaching the laboratory classes, Integrated Laboratory I (PHAR 521) and II (PHAR 611), as well as components of Fundamentals of Medicinal Chemistry (PHAR 522), Biopharmaceutics II (PHAR 532) and Principles of Toxicology (PHAR 802) elective. Dr. Train’s research focuses on educational outcomes such as curricular improvement and enhancing student learning.
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About Brian Train
Dr. Brian C. Train was born in Washington, D.C. in Georgetown Hospital and raised in Mechanicsburg, PA. He attended Washington & Jefferson College and received a B.A. in Biochemistry. During his training at W&J he was on the Dean’s List, swam and played water polo, and was an Academic All-American. After undergraduate training, Dr. Train enrolled in the Biomedical Sciences graduate program at West Virginia University in 2007.
In graduate school, Dr. Train investigated the conformational effects of arylhydrazine modified DNA adducts on DNA structure, specifically in relation to Z-DNA formation. His dissertation project required multi-stage synthesis of DNA adducts and DNA, which was then studied using Nuclear Magnetic Resonance spectroscopy (NMR), Circular Dichroism (CD), Liquid Chromatography-Mass Spectrometry (LC-MS), and Molecular Dynamics simulations (MD). Dr. Train’s project evaluated the potential implications of arylhydrazine carcinogenesis and Z-DNA biological significance. Upon completion of his dissertation, Single C8-Arylguanine Modified Hairpin Oligonucleotides: Synthesis, Conformational Analysis, and Tools for the Investigation of Z-DNA Formation, Dr. Train received a Ph.D. in Pharmaceutical and Pharmacological Sciences.
In addition while in graduate school, Dr. Train was an International Research Experience for Students (IRES) predoctoral fellow in 2009 where he worked at the State Key Laboratory of Supramolecular Structure and Materials at Jilin University in Changchun, Jilin, P.R. of China. He worked on a project to immobilize DNA on a gold film to quantify single strand binding protein (SSB) affinity for single-strand DNA using Single Molecule Force Microscopy (SMFS). He was also a Biochemistry tutor for the West Virginia University School of Pharmacy, which is how he found his passion for teaching. Dr. Train accepted an instructor position at Marshall University School of Pharmacy in August 2014.
Dr. Train is responsible to teaching the laboratory classes, Integrated Laboratory I (PHAR 521) and II (PHAR 611), as well as components of Fundamentals of Medicinal Chemistry (PHAR 522), Biopharmaceutics II (PHAR 532) and Principles of Toxicology (PHAR 802) elective. Dr. Train’s research focuses on educational outcomes such as curricular improvement and enhancing student learning.