This study examined how Bible teachers, involvement in leadership in school-wide spiritual activities, and personal school-sponsored spiritual activities were related to students’ relationship with God and their denominational loyalty. Data were obtained from seniors in 19 Seventh-day Adventist academies. Students’ intention to remain in the Seventh-day Adventist church after they finish high school or leave their parents’ home (denominational loyalty) was explained by their involvement and leadership in school-sponsored spiritual activities and the influence of their Bible teacher. However, the effect of these variables on denominational loyalty was primarily due to the extent that they affected the students’ relationship with God.