|2012 - Present||Associate Professor, Nova Southeastern University ‐ Halmos College of Natural Sciences and Oceanography, Department of Biological Sciences|
Professional Service and Affiliations
|2017 - Present||TE Symposium 2018 Committee Member, Tiny Earth||2014 - Present||Partner Instructor, Tiny Earth (TE)|
- UNIV 1012L - First Year Seminar: Do Microorganisms Define Our Identity?
- HONR 2010 - Germs and Their Power Over Humanity
- ENVS 3101 - Introduction to Public Health
- BIOL 4950 - Internship in Biology
- BIOL 3450 - Virology
- BIOL 3400 - Microbiology
- BIOL 1500 - Biology I/Lab
|2000 - 2003||Postdoctoral Fellow, Harvard Medical School ‐ Department of Microbiology and Immunobiology|
|2000||Ph.D. Microbiology, University of Maryland at College Park|
|1993||B.S. Microbiology, University of Maryland at College Park|
Research Works (10)
Telithromycin. Fresh from the Pipeline Nature Reviews Drug Discovery (2004)
In April 2004, telithromycin (Ketek; Aventis), the first of a new class of antibacterial drugs derived from macrolides, was approved by the US FDA for the treatment of several respiratory-tract infections. After a delay in ...
Atazanavir Sulfate. Fresh from the Pipeline Nature Reviews Drug Discovery (2003)
In June 2003, atazanavir sulphate (Reyataz; Bristol-Myers Squibb) — the first once-daily HIV-1 protease inhibitor — was approved by the US FDA for the treatment of HIV-1 infection in combination with other antiretroviral agents. Will ...
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1 Journal of Virology (2003)
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies whose binding to gp120 is enhanced by CD4 binding (CD4i antibodies) are generally considered nonneutralizing for primary HIV-1 isolates. However, a novel CD4i-specific Fab fragment, X5, has recently ...
CD4 binding site antibodies inhibit human immunodeficiency virus (HIV-1) gp120 envelope glycoprotein interaction with CCR5 Journal of Virology (2003)
The human immunodeficiency virus type 1 (HIV-1) gp120 exterior glycoprotein is conformationally flexible. Upon binding the host cell receptor, CD4, gp120 assumes a conformation that is able to bind the chemokine receptors CCR5 or CXCR4, ...
Interaction of HIV reverse transcriptase with structures mimicking recombination intermediates Journal of Biological Chemistry (2003)
Interactions between human immunodeficiency virus (HIV) reverse transcriptase (RT) and structures mimicking intermediates proposed to occur during recombination (strand transfer) were investigated. One mechanism proposed for strand transfer is strand exchange in which a homologous ...
In vitro strand transfer from broken RNAs results in mismatch but not frameshift mutations Virology (2000)
An in vitro system to compare the fidelity of strand transfers from truncated vs full-length RNAs was constructed. A donor RNA, on which reverse transcriptase (RT)-directed DNA synthesis was initiated, shared homology with an acceptor ...
Kinetic Analysis of the effect of HIV nucleocapsid protein (NCp) on internal strand transfer reactions Biochemistry (1999)
The mechanism of HIV reverse transcriptase (RT) catalyzed strand transfer synthesis (i.e., switching of the primer to a new template) from internal regions on RNA templates in the presence and absence of HIV nucleocapsid protein ...
High fidelity of internal strand transfer catalyzed by human immunodeficiency virus reverse transcriptase Journal of Biological Chemistry (1998)
A system to study the fidelity of internal strand transfer events was constructed. A donor RNA, on which reverse transcriptase (RT)-directed DNA synthesis was initiated, shared homology with an acceptor RNA, to which DNAs initiated ...
Teaching Works (8)
Science Alive!: Connecting with Elementary Students through Science Exploration Journal of Microbiology & Biology Education (2016)
A novel program called Science Alive! was developed by undergraduate faculty members, K–12 school teachers, and undergraduate students to enrich science, technology, engineering, and mathematics (STEM) literacy at community schools located near the university. The ...