Our research focuses on the area of supramolecular chemistry: the study and
application of non-covalent interactions. These interactions include hydrogen bonding,
aromatic stacking and other electrostatic attractions and repulsions. We are currently
employing these concepts of molecular recognition to explore a wide range of important
questions in areas of biology to materials chemistry. 

2007

Controlled fluorination of FePt nanoparticles: Hydrophobic to superhydrophobic surfaces (with Y Ofir, B Samanta, and P Arumugam), Advanced Materials (2007)

FePt nanoparticles with controlled degree of fluorinated ligands are assembled on surfaces to form higher...

 

The synthesis of a pyrrole-functionalized cyclobis( paraquat-p-phenylene) derivative and its corresponding [2]rotaxane and [2]catenane and their subsequent deposition onto an electrode surface (with G Cooke, LM Daniels, F Cazier, JF Garety, SG Hewage, A Parkin, G Rabani, CC Wilson, and P Woisel), Tetrahedron (2007)

We report the convenient synthesis of a pyrrole-functionalized tetracationic cyclophane, [2]rotaxane, and [2]catenane. X-ray crystallography...

 

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Integrated magnetic bionanocomposites through nanoparticle-mediated assembly of ferritin (with S Srivastava, B Samanta, BJ Jordan, R Hong, Q Xiao, and MT Tuominen), Journal of the American Chemical Society (2007)

Magnetic (FePt) and nonmagnetic (Au) nanoparticles were used to assemble ferritin into near-monodisperse bionanocomposites featuring...

 

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Biomimetic interactions of proteins with functionalized nanoparticies: A thermodynamic study (with M De, CC You, and S Srivastava), Journal of the American Chemical Society (2007)

Gold nanoparticles (NPs) functionalized with L-amino acid-terminated monolayers provide an effective platform for the recognition...

 

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Array-based sensing of proteins using conjugated polymers (with OR Miranda, CC You, R Phillips, IB Kim, PS Ghosh, and UHF Bunz), Journal of the American Chemical Society (2007)

A sensor array comprising six functionalized poly(p-phenyleneethynylene) polymers was constructed and used to detect and...

 

2008

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Efficient Gene Delivery Vectors by Tuning the Surface Charge Density of Amino Acid-Functionalized Gold Nanoparticles (with PS Ghosh, CK Kim, G Han, and NS Forbes), ACS Nano (2008)

Gold colloids functionalized with amino acids provide a scaffold for effective DNA binding with subsequent...

 

Controlled Self-Assembly of Organic Nanowires and Platelets Using Dipolar and Hydrogen-Bonding Interactions (with BJ Jordan, Y Ofir, D Patra, ST Caldwell, A Kennedy, S Joubanian, G Rabani, and G Cooke), Small (2008)

Synergistic dipole-dipole and hydrogen-bonding interactions are used to assemble nanostructured materials. Precipitation of a hydrogen-bonding...

 

Nanoparticle Immobilization on Surfaces via Activatable Heterobifunctional Dithiocarbamate Bond Formation (with MH Park, Y Ofir, B Samanta, P Arumugam, and OR Miranda), Advanced Materials (2008)

A simple and reliable technique has been developed to deposit robust monolayers of different types...

 

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Multiplexed Screening of Cellular Uptake of Gold Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry (with ZJ Zhu, PS Ghosh, OR Miranda, and RW Vachet), Journal of the American Chemical Society (2008)

Gold nanoparticles (AuNPs) are highly promising candidates as drug delivery agents into cells of interest....

 

Applications of Nanoparticles in Biology (with M De and PS Ghosh), Advanced Materials (2008)

The wide variety of core materials available, coupled with tunable surface properties, make nanoparticles an...

 

2009

Fabrication and Functionalization of Supramolecular Microgel Arrays Through Complementary Hydrogen-Bonding Interactions (with X Yu, B Samanta, H Xu, P Arumugam, Y Ofir, and BJ Jordan), Small (2009)

Polymer gels are selectively deposited on a pre-patterned substrate, making a microgel array. The microgel...

 

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Modulation of enzyme-substrate selectivity using tetraethylene glycol functionalized gold nanoparticles (with BJ Jordan, R Hong, G Han, and S Rana), Nanotechnology (2009)

Tetraethylene glycol (TEG) functionalized gold nanoparticles with 2 nm core diameters (AuTEG) enhance α-chymotrypsin (ChT)...

 

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Synergistic Effects of Mutations and Nanoparticle Templating in the Self-Assembly of Cowpea Chlorotic Mottle Virus Capsids (with SE Aniagyei, CJ Kennedy, B Stein, DA Willits, T Douglas, MJ Young, M De, D Srisathiyanarayanan, CC Kao, and B Dragnea), Nano Letters (2009)

A study of the in vitro nanoparticle-templated assembly of a mutant of cowpea chlorotic mottle...

 

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Multimodal drug delivery using gold nanoparticles (with CK Kim and P Ghosh), Nanoscale (2009)

Gold nanoparticles (AuNPs) are promising nanocarriers for therapeutics due to their facile synthesis, ease of...

 

Nanoimprinted Polyethyleneimine: A Multimodal Template for Nanoparticle Assembly and Immobilization (with C Subramani, Y Ofir, D Patra, BJ Jordan, IW Moran, MH Park, and KR Carter), Advanced Functional Materials (2009)

Polyethyleneimine (PEI) is used as a scaffold for integrated top-down/bottom-up fabrication. In this synergistic strategy,...

 

2010

Synthesis and use of self-assembled rhamnolipid microtubules as templates for gold nanoparticles assembly to form gold microstructures (with A Rehman, ZA Raza, ZM Khalid, C Subramani, and I Hussain), Journal of Colloid and Interface Science (2010)

Natural unmodified rhamnolipids are thermally self-assembled into soft microtubules, which can produce gold nanoparticles onto...

 

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Role of Surface Charge Density in Nanoparticle-Templated Assembly of Bromovirus Protein Cages (with MC Daniel, IB Tsvetkova, ZT Quinkert, A Murali, M De, CC Kao, and B Dragnea), ACS Nano (2010)

Self-assembling icosahedral protein cages have potencially useful physical and chemical characteristics for a variety of...

 

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Effect of Nanoparticle Surface Charge at the Plasma Membrane and Beyond (with RR Arvizo, OR Miranda, MA Thompson, CM Pabelick, R Bhattacharya, JD Robertson, YS Prakash, and P Mukherjee), Nano Letters (2010)

Herein, we demonstrate that the surface charge of gold nanoparticles (AuNPs) plays a critical role...

 

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Gold nanoparticle self-assembly promoted by a non-covalent, charge-complemented coiled-coil peptide (with D Ernenwein, P Ghosh, and J Chmielewski), Journal of Materials Chemistry (2010)

Non-covalent interactions between cationic gold nanoparticles and an anionic coiled-coil peptide were harnessed for coiled-coil...

 

Fabrication of Conductive Microcapsules via Self-Assembly and Crosslinking of Gold Nanowires at Liquid-Liquid Interfaces (with D Patra, N Malvankar, E Chin, M Tuominen, and ZY Gu), Small (2010)

Terpyridine-functionalized Au nanowires (NWs) are self-assembled at an oil–water interface via metal-mediated crosslinking. The conductivity...