Dr. Rajesh Nagarajan is an Assistant Professor for the Department of Chemistry and
Biochemistry. He earned his Ph.D. from Wesleyan University and completed a Postdoctoral
fellowship at Johns Hopkins University. His many research interests have included
bacterial resistance enzymes, quorum sensing, and biofilm inhibitors. Dr. Nagarajan has
received several grants from such funders as the National Science Foundation, Research
Corporation, and the Camille and Henry Dreyfus Foundation. He has also served on a
variety of university committees and was responsible for developing a research program
involving undergraduates on designing inhibitors for Pseudomonas aeruginosa biofilms. Dr.
Nagarajan has published in Biochemistry, Chemical Reviews, and Journal of Organic
Chemistry.

Articles

Link

Kinetics of Reactions of the Actinomadura R39 DD-Peptidase with Specific Substrates (with S. A. Adediran, Ish Kumar, Eric Sauvage, and R. F. Pratt), Biochemistry (2011)

The Actinomadura R39 DD-peptidase catalyzes the hydrolysis and aminolysis of a number of small peptides...

 

Unmasking Anticooperative DNA-Binding Interactions of Vaccinia DNA Topoisomerase I (with James T. Stivers), Biochemistry (2007)

Vaccinia DNA topoisomerase (vTopo) catalyzes highly specific nucleophilic substitution at a single phosphodiester linkage in...

 

OpenURL

Probing Enzyme Phosphoester Interactions by Combining Mutagenesis and Chemical Modification of Phosphate Ester Oxygens (with James T. Stivers), Chemical Reviews (2006)

Proteins, nucleic acids, lipids, and various other smaller biomolecules are united by the presence of...

 

Presentations

Chemical Tools to Interrupt Bacterial Communication, Western Carolina University, The Department of Chemistry & Physics (2010)

Abstract: A major hurdle in the treatment of bacterial infections is the rapid emergence of...