Dissipative structure theory and synergetics have far-reaching implications for self-organizing phenomena in many diverse fields. This article attempts to apply them in the management of information systems. It begins with a brief review of dissipative structure theory and synergetics, and then demonstrates why they could be applied in information systems. Orderliness is pervasive and of central importance in the operation of information systems. Information science can be regarded as a science about knowledge ordering with the goal of making information more accessible to potential users. Five types of entropy in information systems are analyzed. The relationship between dissipative structure theory and traditional management theories are also discussed. Implications for the management of information systems include: maintaining the system in the state of non-equilibrium, openness towards change, stimulating dynamic cooperative behavior, and selectively amplifying fluctuation. © 1996 John Wiley & Sons, Inc.