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Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan.
Reviews on Environmental Health
  • Fujio Kayama, Jichi Medical University, Shimono, Tochigi, Japan
  • Zafar Fatmi, Aga Khan University
  • Akihiko Ikegami, Jichi Medical University, Shimono, Tochigi, Japan
  • Atsuko Mizuno, Jichi Medical University, Shimono, Tochigi, Japan
  • Mayumi Ohtsu, Jichi Medical University, Shimono, Tochigi, Japan
  • Nathern Mise, Jichi Medical University, Shimono, Tochigi, Japan
  • Xiaoyi Cui, Jichi Medical University, Shimono, Tochigi, Japan
  • Masanori Ogawa, Jichi Medical University, Shimono, Tochigi, Japan
  • Takako Sakamoto, Jichi Medical University, Shimono, Tochigi, Japan
  • Yoshiko Nakagi, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
  • Takahiko Yoshida, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
  • Ambreen Sahito, Aga Khan University
  • Shahla Naeem, Aga Khan University
  • Kulsoom Ghias, Aga Khan University
  • Hina Saeed Zuberi, Aga Khan University
  • Kanwal Tariq, Aga Khan University
  • Yayoi Kobayashi, National Institute of Environmental Studies, Tsukuba, Ibaraki, Japan
  • Keiko Nohara, National Institute of Environmental Studies, Tsukuba, Ibaraki, Japan
Publication Date
3-1-2016
Document Type
Article
Disciplines
Abstract

AIM:

Exposure assessment of lead (Pb) and Arsenic (As) from food, water, and house dust intake were assessed among pregnant women, their children and fetuses in Pakistan and Japan, as well as their body burden of the metals in their blood. METHOD:

Fifty families which included a pregnant woman, a fetus and the 1-3-year-old siblings were recruited in Karachi and Khairpur in Pakistan, and Shimotsuke and Asahikawa in Japan, respectively. Their dietary exposure to Pb and As was measured in 3-day food duplicates and drinking water by ICP-MP. Pb in house dust and respirable dust was evaluated with an energy dispersive X-ray fluorescence spectrometry. Non-radioactive isotope Pb profiles of blood specimens will be compared with those of the exposure origins, such as food duplicates, respirable house dust, the soils nearby, and gasoline. RESULTS:

Judging from the data collected and analyzed so far, contribution from dietary intake is highly correlated to higher body burden of Pb among Pakistani mothers. Additional data analyses will reveal the status of Pb and As body burden in Pakistani mothers, fetuses and their siblings, and causal sources of high body burden is delineated by Pb isotope profile analysis of different sources of Pb exposure.

Citation Information
Fujio Kayama, Zafar Fatmi, Akihiko Ikegami, Atsuko Mizuno, et al.. "Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan." Reviews on Environmental Health Vol. 31 Iss. 1 (2016) p. 33 - 35
Available at: http://works.bepress.com/zafar_fatmi/79/