The notions of rectifying subspaces and of rectifying submanifolds were introduced in [B.-Y. Chen, Int. Electron. J. Geom 9 (2016), no. 2, 1–8]. More precisely, a submanifold in a Euclidean m-space Em is called a rectifying submanifold if its position vector field always lies in its rectifying subspace. Several fundamental properties and classification of rectifying submanifolds in Euclidean space were obtained in [B.-Y. Chen, op. cit.]. In this present article, we extend the results in [B.-Y. Chen, op. cit.] to rectifying space- like submanifolds in a pseudo-Euclidean space with arbitrary codimension. In particular, we completely classify all rectifying space-like submanifolds in an arbitrary pseudo-Euclidean space with codimension greater than one.