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Article
Gas Chromatography-High Resolution Tandem Mass Spectrometry Using a GC-APPI-LIT Orbitrap for Complex Volatile Compounds Analysis
Mass Spectrometry Letters
  • Young Jin Lee, Iowa State University
  • Erica A. Smith, Iowa State University
  • Ji Hyun Jun, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
1-1-2012
DOI
10.5478//MSL.2012.3.2.29
Abstract

A new approach of volatile compounds analysis is proposed using a linear ion trap Orbitrap mass spectrometer coupled with gas chromatography through an atmospheric pressure photoionization interface. In the proposed GC-HRMS/MS approach, direct chemical composition analysis is made for the precursor ions in high resolution MS spectra and the structural identifications were made through the database search of high quality MS/MS spectra. Successful analysis of a complex perfume sample was demonstrated and compared with GC-EI-Q and GC-EI-TOF. The current approach is complementary to conventional GC-EI-MS analysis and can identify low abundance co-eluting compounds. Toluene co-sprayed as a dopant through API probe significantly enhanced ionization of certain compounds and reduced oxidation during the ionization.

Copyright Owner
Lee et al.
Language
en
File Format
application/pdf
Citation Information
Young Jin Lee, Erica A. Smith and Ji Hyun Jun. "Gas Chromatography-High Resolution Tandem Mass Spectrometry Using a GC-APPI-LIT Orbitrap for Complex Volatile Compounds Analysis" Mass Spectrometry Letters Vol. 3 Iss. 2 (2012) p. 29 - 38
Available at: http://works.bepress.com/youngjin-lee/13/