The purpose of this study was to propose and test an affect-based model of tourists’ pro-environmental behavior. The participants in this study were travelers in the U.S. (N=250) collected from an online questionnaire survey. Structural equation modeling (SEM) was used to analyze the data and validate the proposed model. The results show that the five dimensions of place meanings have different influences on place attachment components (i.e., place dependence, place identification and affective bond). Furthermore, the three components of place attachment construct influence tourists’ pro-environmental behavior in various ways. Understanding how destination meanings and attachment influence tourists’ pro-environmental behavior would help destination administrators promote the sustainable development of tourism.