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Selected Works of Yana Sandlers
Article
A Protocol for Metabolic Characterization of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (iPS-CM)
MethodsX
  • Alisha House, Cleveland State University
  • Erica Fatica, Cleveland State University
  • Rohan Shah, Cleveland State University
  • Jared Stergar, Cleveland State University
  • Ryan Pearce, Cleveland State University
  • Yana Sandlers, Cleveland State University
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Document Type
Article
Publication Date
1-1-2020
Disciplines
Abstract

© 2019 The Authors Recent advances in human induced pluripotent stem cell-derived cardiomyocytes (iPSCM) field offer a novel platform for modeling cardiac metabolism, heart diseases drug candidates screening and cardiac toxicity assessments. These workflows require a fully functional characterization of iPSCMs. Here we report a step by step protocol for iPSCM metabolic characterization. The described assays cover analysis of small metabolites involved in a vital metabolic pathways.

Creative Commons License
Creative Commons Attribution 4.0 International
DOI
10.1016/j.mex.2019.05.028
Version
Publisher's PDF
Citation Information
Alisha House, Erica Fatica, Rohan Shah, Jared Stergar, et al.. "A Protocol for Metabolic Characterization of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (iPS-CM)" MethodsX Vol. 7 (2020)
Available at: http://works.bepress.com/yana-sandlers/21/