Skip to main content
Article
Recognition and protection of glycosphingolipids by synthetic nanoparticle receptors
Chemical Communications
  • Roshan W. Gunasekara, Iowa State University
  • Yan Zhao, Iowa State University
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
1-1-2019
DOI
10.1039/C9CC01694E
Abstract

Nanoparticle receptors were synthesized through micellar imprinting to bind glycosphingolipids with 20–140 μM binding affinities, meanwhile distinguishing glycan composition, the number of acyl chains, and hydroxylation of acyl chains in the lipids. The strong binding enabled the receptors to protect their target glycolipids dispersed in lipid membranes from enzymatic degradation.

Comments

This article is published as Gunasekara, Roshan W., and Yan Zhao. "Recognition and protection of glycosphingolipids by synthetic nanoparticle receptors." Chemical Communications 55, no. 33 (2019): 4773-4776. DOI: 10.1039/C9CC01694E. Posted with permission.

Creative Commons License
Creative Commons Attribution 3.0
Copyright Owner
The Royal Society of Chemistry
Language
en
File Format
application/pdf
Citation Information
Roshan W. Gunasekara and Yan Zhao. "Recognition and protection of glycosphingolipids by synthetic nanoparticle receptors" Chemical Communications Vol. 55 Iss. 33 (2019) p. 4773 - 4776
Available at: http://works.bepress.com/yan_zhao/77/