Skip to main content
Article
Tuning the Sensitivity of a Foldamer-Based Mercury Sensor by Its Folding Energy
Journal of the American Chemical Society
  • Yan Zhao, Iowa State University
  • Zhenqi Zhong, Iowa State University
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
7-1-2006
DOI
10.1021/ja062001i
Abstract
A fluorescent sensor for Hg2+ was obtained by incorporation of two methionine units into a cholate hexamer and by attaching a Dansyl group at the chain end. Folding could be made highly favorable or unfavorable in different solvents. Because folding was required to bring the sulfur groups together to chelate the mercury ion, binding affinity of the foldamer and, thus, its sensitivity as a sensor, could be tuned over broad ranges (at least 5 orders of magnitude) by solvent changes.
Comments

Reprinted (adapted) with permission from Journal of the American Chemical Society 128 (2006): 9988, doi:10.1021/ja062001i. Copyright 2006 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
Yan Zhao and Zhenqi Zhong. "Tuning the Sensitivity of a Foldamer-Based Mercury Sensor by Its Folding Energy" Journal of the American Chemical Society Vol. 128 Iss. 31 (2006) p. 9988 - 9989
Available at: http://works.bepress.com/yan_zhao/38/