Article
Environmentally Responsive Molecular Baskets: Unimolecular Mimics of Both Micelles and Reversed Micelles
Organic Letters
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
8-1-2004
DOI
10.1021/ol048679p
Abstract
When four facially amphiphilic cholate derivatives are attached to a tetraaminocalixarene scaffold, the resulting molecule responds to environmental changes by rotation of the cholate units. In polar solvents, the molecule adopts a micellelike conformation with the hydrophilic α-faces of the cholates pointing outward. In nonpolar solvents, it turns inside out, assuming a reversed micellelike conformation with the hydrophobic β-faces pointing outward. Switching between the two conformations is driven by solvophobic interactions and is fully reversible.
Copyright Owner
American Chemical Society
Copyright Date
2004
Language
en
File Format
application/pdf
Citation Information
Eui-Hyun Ryu and Yan Zhao. "Environmentally Responsive Molecular Baskets: Unimolecular Mimics of Both Micelles and Reversed Micelles" Organic Letters Vol. 6 Iss. 18 (2004) p. 3187 - 3189 Available at: http://works.bepress.com/yan_zhao/31/
Reprinted (adapted) with permission from Organic Letters (2004): 3187, doi:10.1021/ol048679p. Copyright 2004 American Chemical Society.