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Article
Facile Synthesis of Multivalent Water-Soluble Organic Nanoparticles via “Surface Clicking” of Alkynylated Surfactant Micelles
Macromolecules
  • Shiyong Zhang, Iowa State University
  • Yan Zhao, Iowa State University
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
4-1-2010
DOI
10.1021/ma100497k
Abstract
Multivalent interactions occur frequently between biological entities.1 When strong binding is not achievable with a single receptor-ligand pair, multivalency, or simultaneous binding between multiple receptors and ligands, becomes an effective strategy to enhance the binding. Significant efforts have been devoted in recent years to synthetic multivalent ligands and their interactions with biological hosts.2 Two of the most widely used scaffolds in multivalency are dendrimers and gold nanoparticles protected with functionalized thiols.
Comments

Reprinted (adapted) with permission from Macromolecules 43 (2010): 4020, doi:10.1021/ma100497k. Copyright 2010 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
Shiyong Zhang and Yan Zhao. "Facile Synthesis of Multivalent Water-Soluble Organic Nanoparticles via “Surface Clicking” of Alkynylated Surfactant Micelles" Macromolecules Vol. 43 Iss. 9 (2010) p. 4020 - 4022
Available at: http://works.bepress.com/yan_zhao/15/