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Presentation
Luciferase gene transfection mediated by cationic liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles
243rd American Chemical Society (ACS) National Meeting & Exposition
  • Xin Liu, University of the Pacific
  • Yu Zheng, University of the Pacific
  • Nataliya M. Samoshina, University of the Pacific
  • Andreas H. Franz, University of the Pacific
  • Vyacheslav V. Samoshin, University of the Pacific
  • Xin Guo, University of the Pacific
Document Type
Poster
Department
Chemistry
Organization
American Chemical Society (ACS)
Location
San Diego, CA
Conference Dates
March 25-March 29, 2012
Date of Presentation
3-28-2012
Disciplines
Abstract

Incorporation of trans-2-aminocyclohexanol-based amphiphiles as helper lipids in DOTAP-cationic liposomes enhances substantially the transfection of the Gaussia luciferase plasmid into HeLa and B16F1 cells. The efficiency of transfection strongly depends on the structure of lipophilic chains and NRR' groups.

Citation Information
Xin Liu, Yu Zheng, Nataliya M. Samoshina, Andreas H. Franz, et al.. "Luciferase gene transfection mediated by cationic liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles" 243rd American Chemical Society (ACS) National Meeting & Exposition (2012)
Available at: http://works.bepress.com/xin-guo/9/