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Presentation
Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain
Faculty of Health and Behavioural Sciences - Papers (Archive)
  • Jiamei Lian, University of Wollongong
  • Xu-Feng Huang, University of Wollongong
  • N Pai, University of Wollongong
  • C Deng, University of Wollongong
RIS ID
64910
Publication Date
1-1-2012
Publication Details

Lian, J., Huang, X., Pai, N. & Deng, C. (2012). Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain. ANS 2012: Australian Neuroscience Society 31st Annual meeting (p. 97). Australia: ANS.

Abstract

Olanzapine is widely used in treating multiple domains of schizophrenia symptoms through its binding profile to various neurotransmitter receptors including a high antagonistic affinity to serotonergic 5-HT2A receptors (5-HT2AR). On the other hand, antagonistic affinity of olanzapine to histamine H1 receptors is a main indicator of its weight gain/obesity side effects.

Citation Information
Jiamei Lian, Xu-Feng Huang, N Pai and C Deng. "Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain" (2012) p. 97
Available at: http://works.bepress.com/xhuang/119/