Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brainFaculty of Health and Behavioural Sciences - Papers (Archive)
AbstractOlanzapine is widely used in treating multiple domains of schizophrenia symptoms through its binding profile to various neurotransmitter receptors including a high antagonistic affinity to serotonergic 5-HT2A receptors (5-HT2AR). On the other hand, antagonistic affinity of olanzapine to histamine H1 receptors is a main indicator of its weight gain/obesity side effects.
Citation InformationJiamei Lian, Xu-Feng Huang, N Pai and C Deng. "Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain" (2012) p. 97
Available at: http://works.bepress.com/xhuang/119/