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Article
Traditional Kava Beverage Consumption and Liver Function Tests in a Predominantly Tongan Population in Hawaii
Clinical Toxicology
  • Amy C. Brown, John A. Burns School of Medicine
  • Janet Onopa, John A. Burns School of Medicine
  • Peter Holck, John A. Burns School of Medicine
  • Pakieli Kaufusi, John A. Burns School of Medicine
  • Derek Kabasawa, University of Hawaiʻi at Mānoa
  • Winston Craig, Andrews University
  • Klaus Dragull, University of Hawaiʻi at Mānoa
  • Arieh M. Levine, University of Hawaiʻi at Mānoa
  • Jonathan D. Baker, University of Hawaiʻi at Mānoa
Document Type
Article
Publication Date
7-1-2007
Keywords
  • Beverage,
  • Hepatotoxicity,
  • Kava,
  • Liver function test,
  • Pacific Islanders
Disciplines
Abstract

Purpose. To determine the effects of traditionally prepared kava beverages on the liver function tests of regular kava beverage consumers in a population of Tongan and non-Tongan residents of Hawaii (Oahu). Methods. The liver function tests of 31 healthy adult kava drinkers were compared against a control group of 31 healthy adult non-kava drinkers. Subjects were recruited from the general population, a kava bar, and Tongan kava drinking circles. The liver function profile included AST, ALT, ALP, GGT, and bilirubin (total and direct). Other tests included total protein, albumin, and screens for viral hepatitis and hemochromatosis when indicated. Results. Chronic kava beverage consumption was associated with elevation of GGT in 65% of the kava drinkers versus 26% in the controls (P =.005). ALP was elevated in 23% of kava drinkers versus 3% in the controls (P =.053). Conclusion. Heavy kava beverage consumption was associated with significantly elevated GGT levels. Copyright © Informa Healthcare.

DOI
10.1080/15563650701365875
First Department
Population Health, Nutrition & Wellness
Citation Information
Amy C. Brown, Janet Onopa, Peter Holck, Pakieli Kaufusi, et al.. "Traditional Kava Beverage Consumption and Liver Function Tests in a Predominantly Tongan Population in Hawaii" Clinical Toxicology Vol. 45 Iss. 5 (2007) p. 549 - 556
Available at: http://works.bepress.com/winston_craig/13/