This study investigates the role that youth-level factors play in predicting help-seeking intentions in a nationally representative sample. Eleven help-seeking intentions were examined separately by target conditions (ADHD and depression), gender, race/ethnicity, and self-reported diagnosed/non-diagnosed in respect to the target conditions, and interaction effects were tested. Using factor analysis, a traditional help-seeking scale was created, which captured four help-seeking items, and predictive power of youth-level factors in accounting for traditional help-seeking was tested. Study findings provide practitioners and researchers with fresh evidence on what youth-level factors are associated with which help-seeking intentions, and illustrate the challenges involved in better understanding the complexity of the help-seeking process among youth in the context of ADHD/Depression. With increased understanding of youth’s perceptions and the complexity of their help-seeking behavior, community-based efforts to develop effective strategies that support active help-seeking behavior and eliminate barriers to appropriate care can have a greater likelihood of success.