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Article
Four-country surveillance of intestinal intussusception and diarrhoea in children
Journal of Paediatrics and Child Health
  • Shally Awasthi, King George Medical University
  • Girdhar Agarwal, Lucknow University
  • Vikas Mishra, King George Medical University
  • Vijay Laxmi Nag, Sanjay Gandhi Postgraduate Institute
  • Hesham Fathey El Sayed, Suez Canal University
  • Antonio Da Cunha, Universidade Federal do Rio de Janeiro
  • Alvaro Madeiro, International Clinical Epidemiology Network
  • Dipty Jain, Government Medical College
  • William Macharia, Aga Khan University
  • James Ndung'u, University of Nairobi
  • Saumya Awasthi, King George Medical University
  • Ashish Wakhlu, King George Medical University
Publication Date
1-1-2009
Document Type
Article
Disciplines
Abstract

Aim: Establishment of baseline epidemiology of intussusception in developing countries has become a necessity with the possibility of reintroduction of rotavirus vaccine. The current study assessed the seasonal trend in cases admitted with intussusceptions and dehydrating acute watery diarrhoea in children aged 2 months to 10 years.

Methods: In a prospective surveillance study, teaching and research hospital sites in India (Lucknow and Nagpur), Brazil (Fortazela), Egypt (Ismailia) and Kenya (Nairobi) established a surveillance where a network of hospitals with surgical facilities catered to a reference population of about 1-2 million for reporting of intussusception. One large hospital per site also recruited admitted cases of acute watery diarrhoea.

Results: From April 2004 to March 2006, 173 and 2346 cases of intussusception and diarrhoea, respectively, were recruited. Cases of intussusception had no apparent seasonality. Most cases of intussusception (61.3%) (107/173) were in the ≤1 year age group, with males comprising 68.8% (119/173) of all cases. Hospital mortality of intussusception was 4.2% (4/96). Cases of diarrhoea peaked in March, with 56.6% (1328/2346) of admitted cases being males. Majority (83.1%) of cases of diarrhoea had received antibiotics, and the hospital mortality was 0.8% (18/2280).

Conclusion: Intussusception in the four participating countries exhibited no seasonal trend. We found that it is feasible to establish a surveillance network for intussusception in developing countries. Future efforts must define population base before the introduction of rotavirus vaccine and continue for some years thereafter. © 2009 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Citation Information
Shally Awasthi, Girdhar Agarwal, Vikas Mishra, Vijay Laxmi Nag, et al.. "Four-country surveillance of intestinal intussusception and diarrhoea in children" Journal of Paediatrics and Child Health Vol. 45 Iss. 3 (2009) p. 82 - 86
Available at: http://works.bepress.com/william_macharia/32/