Skip to main content
Article
Sensitivity of perianal tape impressions to diagnose pinworm (Syphacia spp.) infections in rats (Rattus norvegicus) and mice (Mus musculus)
Journal of the American Association for Laboratory Animal Science : JAALAS (2009)
  • William Allen Hill, University of Tennessee, Knoxville
  • Mildred M. Randolph, University of Tennessee Health Science Center
  • Timothy D. Mandrell, University of Tennessee Health Science Center
Abstract
We determined the sensitivity of perianal tape impressions to detect Syphacia spp. in rats and mice. We evaluated 300 rat and 200 mouse perianal impressions over 9 wk. Pinworm-positive perianal tape impressions from animals with worm burdens at necropsy were considered as true positives. Conversely, pinworm-negative perianal tape impressions from animals with worm burdens were considered false negatives. The sensitivity of perianal tape impressions for detecting Syphacia muris infections in rats was 100%, and for detecting Syphacia obvelata in mice was 85.5%. Intermittent shedding of Syphacia obvelata ova is the most probable explanation for the decreased sensitivity rate we observed in mice. We urge caution in use of perianal tape impressions alone for Syphacia spp. screening in sentinel mice and rats.
Publication Date
July, 2009
Citation Information
William Allen Hill, Mildred M. Randolph and Timothy D. Mandrell. "Sensitivity of perianal tape impressions to diagnose pinworm (Syphacia spp.) infections in rats (Rattus norvegicus) and mice (Mus musculus)" Journal of the American Association for Laboratory Animal Science : JAALAS Vol. 48 Iss. 4 (2009)
Available at: http://works.bepress.com/william_hill/5/