Article
Visualising Protein Interaction Networks With Power Graphs
BMC Systems Biology
(2007)
Abstract
Currently, much research is devoted to the study of protein interaction networks. Novel high-throughput technologies produce large networks, which are complemented by interactions manually or automatically extracted from scientific articles. While the structure of these networks has been widely studied, their visualization remains an unsolved problem. Here, we combine both. Through an understanding of the modular nature of the networks we are able to define a novel visualization and layout. The key idea of the approach is the identification of modules, which form the complex core of these networks and which share many interaction partners. The corresponding edges to these partners are aggregated and lead to a reduction of edges to be laid out.
Keywords
- Interaction Partner,
- Biological Network,
- Complex Core,
- Protein Interaction Network,
- Underlying Structure
Disciplines
Publication Date
May 8, 2007
DOI
10.1186/1752-0509-1-S1-P51
Publisher Statement
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Citation Information
Loïc Royer, Matthias Reimann, Bill Andreopoulos and Michael Schroeder. "Visualising Protein Interaction Networks With Power Graphs" BMC Systems Biology Vol. 1 Iss. P51 (2007) Available at: http://works.bepress.com/william-andreopoulos/29/