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Alternative Grafts in Anterior Cervical Fusion.
Clinical neurology and neurosurgery
  • Fangxiang Chen
  • Wenzhuan He, Lehigh Valley Health Network
  • Kelly Mahaney
  • Jennifer Noeller
  • Nakhle E Mhanna
  • Stephen Viljoen
  • James Torner
  • Patrick W Hitchon
Publication/Presentation Date
OBJECTIVE: The present retrospective study was conducted to compare the clinical and radiographic outcomes in patients undergoing anterior cervical discectomy with fusion (ACDF) using carbon fiber reinforced polymer (CFRP) cages, or allograft. METHODS: We retrospectively reviewed cases of ACDF using allograft in 20 patients, and CFRP in 19 who had sequential radiographs before and after surgery, and at 1 year. RESULTS: There were no apparent significant differences between the 2 groups in age (p=0.057), gender (p=0.635), or complications (p=0.648). At 12 months, there were no cases of construct failure, and fusion appeared to have been achieved in patients of both groups. Lordosis was increased significantly in both groups after surgery (p0.21). This increase in height was greatest in magnitude immediately after surgery, and declined with the passage of time. There was no detectable health-related quality of life difference between allograft and CFRP group after surgery (p>0.05). CONCLUSION: The present study demonstrates that CFRP cages appear to have comparable fusion rates, restoration of lordosis and disc space height, and complication rates to patients who undergo ACDF with allograft.
Document Type
Citation Information

CHEN, F; et al. Alternative grafts in anterior cervical fusion. Clinical Neurology And Neurosurgery. Netherlands, 115, 10, 2049-2055, Oct. 2013. ISSN: 1872-6968