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Options in Treating Trigeminal Neuralgia: Experience With 195 Patients.
Clinical Neurology And Neurosurgery
  • Patrick W Hitchon
  • Marshall Holland
  • Jennifer Noeller
  • Mark C Smith
  • Toshio Moritani
  • Nivedita Jerath
  • Wenzhuan He, MD, Lehigh Valley Health Network
Publication/Presentation Date

OBJECTIVE: For patients with medically unresponsive trigeminal neuralgia (TN), surgical options include microvascular decompression (MVD), radiofrequency rhizotomy (RF), and stereotactic radiosurgery (SRS). In an attempt to identify the risks and benefits and cost inherent with each of the three modalities, we performed a retrospective review of our experience with 195 cases of TN treated over the past 15 years.

METHODS: Since 2001, 195 patients with previously untreated TN were managed: with MVD in 79, RF in 36, and SRS in 80. All patients reported herein underwent preoperative MRI. Women outnumbered men 122/73 (p=0.045). Follow-up after surgery was 32±46months.

RESULTS: The patients qualifying for MVD were generally healthier and younger, with a mean age±SD of 57±14, compared to those undergoing RF (75±15) or SRS (73±13, p

CONCLUSION: MVD for TN is the treatment least likely to fail or require additional treatment. Patients who underwent MVD were younger than those undergoing RF or SRS. The highest rate of recurrence of TN was encountered in patients undergoing RF (64%). Facial numbness was least likely to occur with MVD (16%) compared to RF and SRS (50% and 36% respectively).

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Citation Information

Hitchon, P. W., Holland, M., Noeller, J., Smith, M. C., Moritani, T., Jerath, N., & He, W. (2016). Options in treating trigeminal neuralgia: Experience with 195 patients. Clinical Neurology And Neurosurgery, 149166-170. doi:10.1016/j.clineuro.2016.08.016